Version 1
: Received: 29 December 2023 / Approved: 3 January 2024 / Online: 4 January 2024 (05:43:23 CET)
How to cite:
Egorov, V.; Rosen, T.; Hill, J.; Khandelwal, M.; Kurtenoks, V.; Francy, B.; Sarvazyan, N. Evaluating the Efficacy of Cervical Tactile Ultrasound Technique as a Predictive Tool for Spontaneous Preterm Birth. Preprints2024, 2024010260. https://doi.org/10.20944/preprints202401.0260.v1
Egorov, V.; Rosen, T.; Hill, J.; Khandelwal, M.; Kurtenoks, V.; Francy, B.; Sarvazyan, N. Evaluating the Efficacy of Cervical Tactile Ultrasound Technique as a Predictive Tool for Spontaneous Preterm Birth. Preprints 2024, 2024010260. https://doi.org/10.20944/preprints202401.0260.v1
Egorov, V.; Rosen, T.; Hill, J.; Khandelwal, M.; Kurtenoks, V.; Francy, B.; Sarvazyan, N. Evaluating the Efficacy of Cervical Tactile Ultrasound Technique as a Predictive Tool for Spontaneous Preterm Birth. Preprints2024, 2024010260. https://doi.org/10.20944/preprints202401.0260.v1
APA Style
Egorov, V., Rosen, T., Hill, J., Khandelwal, M., Kurtenoks, V., Francy, B., & Sarvazyan, N. (2024). Evaluating the Efficacy of Cervical Tactile Ultrasound Technique as a Predictive Tool for Spontaneous Preterm Birth. Preprints. https://doi.org/10.20944/preprints202401.0260.v1
Chicago/Turabian Style
Egorov, V., Brendan Francy and Noune Sarvazyan. 2024 "Evaluating the Efficacy of Cervical Tactile Ultrasound Technique as a Predictive Tool for Spontaneous Preterm Birth" Preprints. https://doi.org/10.20944/preprints202401.0260.v1
Abstract
This study aims to explore the applicability of an innovative cervical tactile ultrasound approach for predicting spontaneous preterm birth (sPTB). Eligible participants were women with low-risk singleton pregnancies in their second trimester, enrolled in this prospective observational study. A Cervix Monitor (CM) device was designed with a vaginal probe comprising four tactile sensors and a single ultrasound transducer operating at 5 MHz. The probe enabled the application of controllable pressure to the external cervical surface, facilitating the acquisition of stress-strain data from both anterior and posterior cervical sectors. These data were used to calculate cervical elasticity, as a stress-to-strain ratio. CM examination data were analyzed for 127 women at 24 - 28 gestational weeks. PTB was observed in 6.3% (8 out of 127) of the cases. The preterm group exhibited a lower average cervical stress-to-strain ratio (elasticity) of 0.70±0.26 kPa/mm compared to the term group's 1.63±0.65 kPa/mm, with a significant p-value of 1.1×10-4. Diagnostic accuracy for predicting spontaneous preterm birth based solely on cervical elasticity data was found to be 95.0% (95% CI, 88.5–100.0). These findings suggest that measuring cervical elasticity with the designed tactile ultrasound probe could potentially predict spontaneous preterm birth in a cost-effective manner.
Medicine and Pharmacology, Obstetrics and Gynaecology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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