Version 1
: Received: 27 December 2023 / Approved: 28 December 2023 / Online: 28 December 2023 (11:51:57 CET)
How to cite:
Ponphaiboon, J.; Limmatvapirat, S.; Limmatvapirat, C. Anti-Bacterial and Antioxidant Potential of an Ostrich Oil Emulsion. Preprints2023, 2023122190. https://doi.org/10.20944/preprints202312.2190.v1
Ponphaiboon, J.; Limmatvapirat, S.; Limmatvapirat, C. Anti-Bacterial and Antioxidant Potential of an Ostrich Oil Emulsion. Preprints 2023, 2023122190. https://doi.org/10.20944/preprints202312.2190.v1
Ponphaiboon, J.; Limmatvapirat, S.; Limmatvapirat, C. Anti-Bacterial and Antioxidant Potential of an Ostrich Oil Emulsion. Preprints2023, 2023122190. https://doi.org/10.20944/preprints202312.2190.v1
APA Style
Ponphaiboon, J., Limmatvapirat, S., & Limmatvapirat, C. (2023). Anti-Bacterial and Antioxidant Potential of an Ostrich Oil Emulsion. Preprints. https://doi.org/10.20944/preprints202312.2190.v1
Chicago/Turabian Style
Ponphaiboon, J., Sontaya Limmatvapirat and Chutima Limmatvapirat. 2023 "Anti-Bacterial and Antioxidant Potential of an Ostrich Oil Emulsion" Preprints. https://doi.org/10.20944/preprints202312.2190.v1
Abstract
This study explores the development of an oil-in-water (O/W) emulsion with a high concentration of ostrich oil, rich in omega-3, -6, and -9 fatty acids, for potential skincare applications. Utilizing Span and Tween emulsifiers, an optimized O/W emulsion containing 20% w/w ostrich oil and 15% w/w mixed emulsifiers was formulated through homogenization, demonstrating the smallest droplet size (5.01 ± 0.43 μm) and appropriate zeta potential (-32.22 mV). The emulsion exhibited antioxidant and antibacterial properties against Staphylococcus aureus, suggesting its suitability for skincare. Stability tests over 6 months at varying temperatures (4 °C, 25 °C, 45 °C) confirmed the emulsion's physical and microbial stability, emphasizing its potential for topical applications. Despite slight changes in acid values (AV) and peroxide values (PV), results remained within acceptable limits. Cytotoxicity assessments on human dermal fibroblasts indicated the emulsion's safety, supporting its suitability for skin application. The emulsion demonstrated antibacterial efficacy against S. aureus and enhanced antioxidant activity compared to ostrich oil alone. The study underscores the importance of emulsification in optimizing the efficacy and stability of ostrich oil in skincare formulations, offering valuable insights for practical applications where stability is critical.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
