Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Near-infrared Spectroscopy for Brain and Breast Imaging

Version 1 : Received: 25 December 2023 / Approved: 26 December 2023 / Online: 26 December 2023 (07:47:29 CET)

How to cite: Buckley, D. Near-infrared Spectroscopy for Brain and Breast Imaging. Preprints 2023, 2023121913. https://doi.org/10.20944/preprints202312.1913.v1 Buckley, D. Near-infrared Spectroscopy for Brain and Breast Imaging. Preprints 2023, 2023121913. https://doi.org/10.20944/preprints202312.1913.v1

Abstract

Near-infrared spectroscopy (NIRS) has become a key modality in medical imaging, finding application in both brain and breast imaging. This paper discusses the current trends in NIRS for brain and breast imaging, exploring advances in multi-modal integration with modalities such as functional magnetic resonance imaging (fMRI) and electroencephalography (EEG). Challenges related to spatial resolution, depth sensitivity, and the impact of extracerebral tissues on signal specificity are examined. In addition, ongoing efforts to enhance hemodynamic measurements’ quantitative accuracy. Challenges, including limited spatial resolution and tissue heterogeneity, are discussed. The discussion extends to diffuse optical tomography and ongoing instrumentation development, clinical trials and studies validating NIRS diagnostic efficacy in breast imaging. The paper emphasizes the need for standardization, integration into routine clinical practice, and motivates for future work.

Keywords

Near-infrared spectroscopy; Brain imaging; Breast imaging; Brain activity; Cancer; Diffuse Optical; Tomography; fNIRS

Subject

Engineering, Bioengineering

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