Version 1
: Received: 18 December 2023 / Approved: 19 December 2023 / Online: 19 December 2023 (10:16:51 CET)
How to cite:
GÖKTÜRK, I.; YILMAZ, F.; Aşır, S.; TÜRKMEN, D.; Denizli, A. Molecularly imprinted biomimetic SPR sensor decorated with gold nanoparticles
for selective and sensitive detection of bisphenol A. Preprints2023, 2023121431. https://doi.org/10.20944/preprints202312.1431.v1
GÖKTÜRK, I.; YILMAZ, F.; Aşır, S.; TÜRKMEN, D.; Denizli, A. Molecularly imprinted biomimetic SPR sensor decorated with gold nanoparticles
for selective and sensitive detection of bisphenol A. Preprints 2023, 2023121431. https://doi.org/10.20944/preprints202312.1431.v1
GÖKTÜRK, I.; YILMAZ, F.; Aşır, S.; TÜRKMEN, D.; Denizli, A. Molecularly imprinted biomimetic SPR sensor decorated with gold nanoparticles
for selective and sensitive detection of bisphenol A. Preprints2023, 2023121431. https://doi.org/10.20944/preprints202312.1431.v1
APA Style
GÖKTÜRK, I., YILMAZ, F., Aşır, S., TÜRKMEN, D., & Denizli, A. (2023). Molecularly imprinted biomimetic SPR sensor decorated with gold nanoparticles
for selective and sensitive detection of bisphenol A. Preprints. https://doi.org/10.20944/preprints202312.1431.v1
Chicago/Turabian Style
GÖKTÜRK, I., DENİZ TÜRKMEN and Adil Denizli. 2023 "Molecularly imprinted biomimetic SPR sensor decorated with gold nanoparticles
for selective and sensitive detection of bisphenol A" Preprints. https://doi.org/10.20944/preprints202312.1431.v1
Abstract
MIPs inspired by antigen-antibody interactions have received substantial interest as a biomimetic artificial receptor system in environmental applications. Herein, we present a molecularly imprinted surface plasmon resonance (SPR) sensor integrated with Au nanoparticles for the identification of bisphenol A (BPA), an endocrine-disrupting chemical. The synthetic wastewater samples were analyzed to ensure the method's reliability and feasibility. Under ideal conditions, the suggested approach performed well in terms of analytical performance to BPA, with a wide linear range of 0.1 to 10 ppb and LOD of 10 ng/L. The sensor results and the Langmuir adsorption model have good agreement. It has also been shown that repeated use of the biosensor can be achieved. According to selectivity studies, BPA adsorbed within the imprinted cavities favorably compared to 4-nitrophenol and phenol.
The produced BPA-imprinted SPR sensor provides improved sensitivity based on the signal amplification strategy, unconjugated sensing without the need for labeling, real-time sensing, low sample consumption rates, quantifiable assessment, and very good kinetic rate constant calculation in actual samples. Also, because the produced sensor is reusable with relative standard deviations (RSD)<1.25, indicating the sensor's accuracy, the SPR-based biomimetic BPA sensor is simple to practice and may be an economical option.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
