Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Altering Selectivity in the Tug-of-War Mechanism by Mechanochemistry –with an Explanation of Catch Bond Behavior

Version 1 : Received: 15 December 2023 / Approved: 15 December 2023 / Online: 15 December 2023 (15:16:26 CET)

How to cite: Quapp, W.; Bofill, J.M. Altering Selectivity in the Tug-of-War Mechanism by Mechanochemistry –with an Explanation of Catch Bond Behavior. Preprints 2023, 2023121203. https://doi.org/10.20944/preprints202312.1203.v1 Quapp, W.; Bofill, J.M. Altering Selectivity in the Tug-of-War Mechanism by Mechanochemistry –with an Explanation of Catch Bond Behavior. Preprints 2023, 2023121203. https://doi.org/10.20944/preprints202312.1203.v1

Abstract

We discuss slip bonds, catch bonds and the tug-of-war mechanism using mathematical arguments. We propose simple 2-dimensional surface models to demonstrate how the potential energy surface of a molecule under an external force behaves. Examples are selectines. Catch bonds in particular are explained in more detail. We demonstrate that Newton trajectories are a powerful tool to describe these phenomena. Newton trajectories form the theoretical background of Mechanochemistry.

Keywords

Slip bonds; catch bonds; tug-of-war-mechanism; selectines; Newton trajectories

Subject

Biology and Life Sciences, Biochemistry and Molecular Biology

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