Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

The Longitudinal Association of Egg Consumption With Cognitive Function in Older Men and Women: The Rancho Bernardo Study

Version 1 : Received: 13 December 2023 / Approved: 13 December 2023 / Online: 14 December 2023 (03:21:55 CET)

A peer-reviewed article of this Preprint also exists.

Kritz-Silverstein, D.; Bettencourt, R. The Longitudinal Association of Egg Consumption with Cognitive Function in Older Men and Women: The Rancho Bernardo Study. Nutrients 2024, 16, 53. Kritz-Silverstein, D.; Bettencourt, R. The Longitudinal Association of Egg Consumption with Cognitive Function in Older Men and Women: The Rancho Bernardo Study. Nutrients 2024, 16, 53.

Abstract

This study examines the prospective association of egg consumption with multiple domains of cognitive function in older, community-dwelling men and women followed 16.3 years. Participants were 617 men and 898 women from the Rancho Bernardo Cohort aged 60 and older who were surveyed about egg intake/week in 1972-74, and attended a 1988-91 research visit when cognitive function was assessed with 12 tests. Analyses showed that egg intake ranged from 0-24/week (means: men=4.23.2, women=3.52.7, p<0.0001). In men, covariate-adjusted regressions showed egg intake was associated with better performance on Buschke total (p=0.04), long-term (p=0.02) and short-term (p=0.05) recall. No significant associations were observed in women (p’s>0.05). Analyses in those <60y at in 1972-74 showed egg intake was positively associated with scores on Heaton copying(p<.04) and the Mini-Mental Status Exam(MMSE;p<.02) in men, and category fluency(p<0.05) in women. Egg intake was not significantly associated with odds of poor performance on MMSE, Trails B, or category fluency in either sex. These reassuring findings suggest there are no long-term detrimental effects of egg consumption on multiple cognitive function domains, and for men, there may be beneficial effects for verbal episodic memory. Egg consumption in middle-age may also be related to better cognitive performance later in life.

Keywords

cognitive function; egg consumption; impaired cognitive function; longitudinal; memory; older men and women

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

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