Ba, A.; Diop, G.L.; Ndiaye, M.; Dione, M.; Lo, M.M. First Report of the Emergence of Peste des Petits Ruminants Lineage IV Virus in Senegal. Viruses2024, 16, 305.
Ba, A.; Diop, G.L.; Ndiaye, M.; Dione, M.; Lo, M.M. First Report of the Emergence of Peste des Petits Ruminants Lineage IV Virus in Senegal. Viruses 2024, 16, 305.
Ba, A.; Diop, G.L.; Ndiaye, M.; Dione, M.; Lo, M.M. First Report of the Emergence of Peste des Petits Ruminants Lineage IV Virus in Senegal. Viruses2024, 16, 305.
Ba, A.; Diop, G.L.; Ndiaye, M.; Dione, M.; Lo, M.M. First Report of the Emergence of Peste des Petits Ruminants Lineage IV Virus in Senegal. Viruses 2024, 16, 305.
Abstract
PPR is a highly contagious viral disease and one of the deadliest affecting wild goats, sheep and small ruminants, however goats are generally more sensitive. The causative agent is the Peste des Petits Ruminants virus (PPRv) which is a single-stranded RNA virus of negative polarity belonging to the Paramyxoviridae family. In February 2020, an active outbreak of PPR was re-ported in a herd of a transhumant farmer in the village of Ngainth Pathé (department of Kounguel, Kaffrine region,Senegal). Of the ten (10) swabs collected from goats, eight (8) came back positive by real-time PCR. The most positive sample was amplified, purified and amplicon sent for sequencing. Phylogenetic analysis showed that the sequence of the PPR virus obtained belonged to lineage IV. These results confirm those found in the latter countries and reinforce the hypothesis of the importance of animal mobility between these neighboring countries. In perspective, following the discovery of this lineage IV in Senegal, a study on its dispersion is underway throughout the national territory. The results that will emerge from this study, asso-ciated with detailed data on animal movements and epidemiological data, will provide appro-priate and effective information to improve PPR surveillance and control strategies with a view to its eradication.
Keywords
Peste des petits ruminants; lineage IV; Molecular characterization; Senegal
Subject
Biology and Life Sciences, Virology
Copyright:
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