Enhancing Breast Cancer Therapy: Nanocarrier-Based Targeted Drug Delivery

Ramendra Pandey; Ruby Dhiman; Nancy Bazad; Riya Mukerjee; Jasmina Vidic; Elcio Leal; V. Samuel Raj; Chung-Ming Chang

doi:10.20944/preprints202312.0632.v1

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preprints.org > biology and life sciences > biology and biotechnology > doi: 10.20944/preprints202312.0632.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Enhancing Breast Cancer Therapy: Nanocarrier-Based Targeted Drug Delivery

^* ,

Version 1 : Received: 8 December 2023 / Approved: 8 December 2023 / Online: 9 December 2023 (08:19:16 CET)

How to cite: Pandey, R.; Dhiman, R.; Bazad, N.; Mukerjee, R.; Vidic, J.; Leal, E.; Raj, V.S.; Chang, C. Enhancing Breast Cancer Therapy: Nanocarrier-Based Targeted Drug Delivery. Preprints 2023, 2023120632. https://doi.org/10.20944/preprints202312.0632.v1 Pandey, R.; Dhiman, R.; Bazad, N.; Mukerjee, R.; Vidic, J.; Leal, E.; Raj, V.S.; Chang, C. Enhancing Breast Cancer Therapy: Nanocarrier-Based Targeted Drug Delivery. Preprints 2023, 2023120632. https://doi.org/10.20944/preprints202312.0632.v1

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MDPI and ACS Style

Pandey, R.; Dhiman, R.; Bazad, N.; Mukerjee, R.; Vidic, J.; Leal, E.; Raj, V.S.; Chang, C. Enhancing Breast Cancer Therapy: Nanocarrier-Based Targeted Drug Delivery. Preprints 2023, 2023120632. https://doi.org/10.20944/preprints202312.0632.v1

APA Style

Pandey, R., Dhiman, R., Bazad, N., Mukerjee, R., Vidic, J., Leal, E., Raj, V.S., & Chang, C. (2023). Enhancing Breast Cancer Therapy: Nanocarrier-Based Targeted Drug Delivery. Preprints. https://doi.org/10.20944/preprints202312.0632.v1

Chicago/Turabian Style

Pandey, R., V. Samuel Raj and Chung-Ming Chang. 2023 "Enhancing Breast Cancer Therapy: Nanocarrier-Based Targeted Drug Delivery" Preprints. https://doi.org/10.20944/preprints202312.0632.v1

Abstract

Breast cancer (BC) is one of the most common types of cancer in women. Triple-negative breast cancer (TNBC), characterized by the absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2), exhibits a highly aggressive phenotype with increased metastasis and resistance to conventional treatments. Nanocarrier technology is consistently employed to overcome limitations associated with traditional breast cancer therapy. The targeted drug delivery approach using nanocarriers enhances bioavailability, prolongs circulation, and facilitates effective drug accumulation at the tumor site through active or passive targeting. Currently, the FDA has approved a few nanocarrier systems, and numerous nano formulations are undergoing preclinical and clinical development for breast cancer targeting. Common nanocarrier types include polymeric micelles, microemulsions, magnetic microemulsions, liposomes, dendrimers, carbon nanotubes, and magnetic nanoparticles (NPs). This review extensively explores the targeting potential of nanocarriers in breast cancer. This study will provide a concise summary of current advances in treatment of breast cancer and diagnostics.

Keywords

Breast cancer; Nanocarriers; Tumor location; Diagnostics

Subject

Biology and Life Sciences, Biology and Biotechnology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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