Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Gene Expression Network Analysis (GENA) – A Biostatistical Method to Unravel Intricate Relationships Between Genes

Version 1 : Received: 6 December 2023 / Approved: 6 December 2023 / Online: 6 December 2023 (10:37:56 CET)

How to cite: Rajamani, D.S.K. Gene Expression Network Analysis (GENA) – A Biostatistical Method to Unravel Intricate Relationships Between Genes. Preprints 2023, 2023120377. https://doi.org/10.20944/preprints202312.0377.v1 Rajamani, D.S.K. Gene Expression Network Analysis (GENA) – A Biostatistical Method to Unravel Intricate Relationships Between Genes. Preprints 2023, 2023120377. https://doi.org/10.20944/preprints202312.0377.v1

Abstract

Deeper understanding of biological processes, disease mechanisms, and prospective therapeutic targets can be attained by Gene Expression Network Analysis (GENA), which offers a potent framework for revealing the intricate regulatory mechanisms controlling gene expression. GENA is a computational method used to understand the intricate interactions and relationships between the genes in a biological system. It entails using network theory, statistical analysis, and gene expression data to pinpoint functional modules, regulatory linkages, and important genes or pathways involved in a particular biological process or illness. This chapter broadly outlines the principles and practice of GENA, to an novice reader and outlines a simple method of performing a GENA using online Rice gene expression datasets available in various websites.

Keywords

network analysis; genetics; gene expression network analysis; plants

Subject

Biology and Life Sciences, Other

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