The Multidisciplinary Approach and Surgical Management of GE Junction Adenocarcinoma

Meher Oberoi; MD Sibat Noor; Eihab Abdelfatah

doi:10.20944/preprints202311.1775.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 27 November 2023 / Approved: 28 November 2023 / Online: 29 November 2023 (04:58:57 CET)

Gastroesophageal (GE) junction adenocarcinoma is an aggressive malignancy of growing incidence and is associated with public health issues such as obesity and GERD. Management has evolved over the last 2 decades to incorporate a multidisciplinary approach including endoscopic intervention, and neoadjuvant chemotherapy/ chemoradiation and minimally invasive or more limited surgical approaches. Surgical approaches include esophagectomy, total gastrectomy, and more recently proximal gastrectomy. This review analyzes the evidence for and applicability of these varied approaches in management as well areas of continued controversy and investigation.

GE junction cancer; Esophagogastric cancer; Gastroesophageal cancer; Esophageal cancer; Gastric cancer; Esophagectomy; Gastrectomy; Proximal gastrectomy

Medicine and Pharmacology, Surgery

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The Multidisciplinary Approach and Surgical Management of GE Junction Adenocarcinoma

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