Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Management of Acute Bronchiolitis in Spoke Hospitals: Analysis and Outcome

Version 1 : Received: 21 November 2023 / Approved: 21 November 2023 / Online: 21 November 2023 (17:18:53 CET)

A peer-reviewed article of this Preprint also exists.

Guidi, C.; Ragusa, N.; Mussinatto, I.; Parola, F.; Luotti, D.; Calosso, G.; Rotondo, E.; Deut, V.; Timeus, F.; Brach del Prever, A.; Berger, M. Management of Acute Bronchiolitis in Spoke Hospitals in Northern Italy: Analysis and Outcome. Diseases 2024, 12, 25. Guidi, C.; Ragusa, N.; Mussinatto, I.; Parola, F.; Luotti, D.; Calosso, G.; Rotondo, E.; Deut, V.; Timeus, F.; Brach del Prever, A.; Berger, M. Management of Acute Bronchiolitis in Spoke Hospitals in Northern Italy: Analysis and Outcome. Diseases 2024, 12, 25.

Abstract

Bronchiolitis is an acute viral infection of the lower respiratory tract that affects infants and young children. Respiratory syncytial virus (RSV) is the most common causative agent, however other viruses can be the reason of the disease. We retrospectively reviewed the clinical features of infants aged less than 12 months referred to our Pediatric Units of Chivasso, Cirié and Ivrea for acute bronchiolitis requiring hospitalization over two consecutive bronchiolitis seasons. Patient-, disease- and treatment related variables were analyzed in this retrospective study. We were able to show how with the high flow oxygen support (HFNC) only a very low number of children (8 out of 192) need to be trasferred to our HUB referral centers. The probability of success were 96% for all patients and 93% for RSV vs. 98% for non-RSV patients (P=NS). Factor associated to failure of treatment were age below 1 months and the failure of HFNC. The wide and increasing use of HFNC in pediatric inpatients improved management of bronchiolitis in Spoke hospitals, reducing transfer to a Hub hospital provided with Intensive Care Units.

Keywords

bronchiolitis; children; respiratory syncytial virus; high flow nasal cannula; acute bronchiolitis

Subject

Medicine and Pharmacology, Pediatrics, Perinatology and Child Health

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