Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Assessment of Standard Surgical Excision Efficacy and Analysis of Recurrence-Associated Factors in 343 Cases of Nasal Basal Cell Carcinoma: a single-center retrospective study

Version 1 : Received: 14 November 2023 / Approved: 14 November 2023 / Online: 15 November 2023 (04:03:17 CET)

A peer-reviewed article of this Preprint also exists.

Baltrušaitytė, K.; Zacharevskij, E.; Pilipaitytė, L.; Braziulis, K.; Petkevičius, A. Assessment of Standard Surgical Excision Efficacy and Analysis of Recurrence-Associated Factors in 343 Cases of Nasal Basal Cell Carcinoma: A Single-Center Retrospective Study. Healthcare 2024, 12, 513. Baltrušaitytė, K.; Zacharevskij, E.; Pilipaitytė, L.; Braziulis, K.; Petkevičius, A. Assessment of Standard Surgical Excision Efficacy and Analysis of Recurrence-Associated Factors in 343 Cases of Nasal Basal Cell Carcinoma: A Single-Center Retrospective Study. Healthcare 2024, 12, 513.

Abstract

In Caucasians, basal cell carcinoma, a type of non-melanoma skin cancer, is most often found on the nose. This presents challenges for surgeons due to anatomical, functional, and aesthetic concerns. The study aimed to evaluate the distribution of tumor localization, size, morphological subtypes, surgical outcomes, radicality levels, and their correlation with recurrence rates. The research utilized data from the Hygiene Institute Health Information Centre. A retrospective analysis encompassed 343 cases of nasal skin cancer over a four-year period from January 1, 2019, to December 31, 2022. The research cohort comprised 252 female and 91 male participants, averaging 75,2 years old. Tumors were most found on the left sidewall of the nose (25.4%) and the dorsum (24.8%). The infiltrative morphological subtype was predominant (70.8%). Standard surgical excision with fasciocutaneous plastic was the preferred surgical procedure. Radical excision was achieved in 79.0% of lesions, while 16.9% were incompletely excised. Non-radically excised tumors exhibited a significantly higher recurrence rate (24.1%) compared to those with radical excision (6.3%). In nasal reconstruction, diverse surgical techniques are essential for precise adaptation based on factors like tumor characteristics and patient needs. Despite surgeons' careful adherence to excision guidelines, the potential for non-radical procedures cannot be entirely eliminated.

Keywords

Basal Cell Carcinoma; non–melanoma skin cancer; recurrence; Standard Surgical Excision

Subject

Medicine and Pharmacology, Dermatology

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