Fernandez, C.J.; Alkhalifah, M.; Afsar, H.; Pappachan, J.M. Metabolic Dysfunction-Associated Fatty Liver Disease and Chronic Viral Hepatitis: The Interlink. Pathogens2024, 13, 68.
Fernandez, C.J.; Alkhalifah, M.; Afsar, H.; Pappachan, J.M. Metabolic Dysfunction-Associated Fatty Liver Disease and Chronic Viral Hepatitis: The Interlink. Pathogens 2024, 13, 68.
Fernandez, C.J.; Alkhalifah, M.; Afsar, H.; Pappachan, J.M. Metabolic Dysfunction-Associated Fatty Liver Disease and Chronic Viral Hepatitis: The Interlink. Pathogens2024, 13, 68.
Fernandez, C.J.; Alkhalifah, M.; Afsar, H.; Pappachan, J.M. Metabolic Dysfunction-Associated Fatty Liver Disease and Chronic Viral Hepatitis: The Interlink. Pathogens 2024, 13, 68.
Abstract
Metabolic dysfunction-associated fatty liver disease (MAFLD) has now affected nearly one third of global population and became the number one cause of chronic liver disease in the world because of the obesity pandemic. Chronic hepatitis resulting from hepatitis B virus (HBV) and hepatitis C virus (HCV) also remain significant challenges to liver health even in the 21st century. The coexistence of MAFLD and chronic viral hepatitis can markedly alter the disease course of individual diseases and can complicate the management of each of these disorders. Thorough understanding of the pathobiological interlink and interactions between MAFLD and these two chronic viral hepatitis infections are crucial for appropriate management of patients. We update these interlinks in this comprehensive clinical review.
Keywords
metabolic dysfunction-associated fatty liver disease (MAFLD); chronic viral hepatitis; Hepatitis B virus (HBV); Hepatitis C virus; Hepatic Fibrosis; Cirrhosis; and Hepatocellular carcinoma
Subject
Medicine and Pharmacology, Endocrinology and Metabolism
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
