Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Rare Neurological Disorder Unveiled: CLIPPERS Disease - A Case Report

Version 1 : Received: 8 November 2023 / Approved: 8 November 2023 / Online: 8 November 2023 (15:42:44 CET)

How to cite: Shah, S.; Gami, V.; Desai, D.; Teraiya, T. Rare Neurological Disorder Unveiled: CLIPPERS Disease - A Case Report. Preprints 2023, 2023110568. https://doi.org/10.20944/preprints202311.0568.v1 Shah, S.; Gami, V.; Desai, D.; Teraiya, T. Rare Neurological Disorder Unveiled: CLIPPERS Disease - A Case Report. Preprints 2023, 2023110568. https://doi.org/10.20944/preprints202311.0568.v1

Abstract

CLIPPERS which stand for Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids, is a chronic inflammatory disorder of the central nervous system. The aetiology of CLIPPERS remains unclear, although its pathogenesis shows immune-mediated processes. The diagnosis of CLIPPERS is challenging without a specific biomarker hence, it is important to consider if both the clinical and radiological features are consistent with the diagnosis, or rather any other disease that mimics CLIPPERS. The Authors present a case of a 40-year-old Female patient diagnosed with CLIPPERS syndrome in India. Differential diagnosis, clinical and MRI characteristics of CLIPPERS syndrome, and treatment approaches are discussed.

Keywords

Brain Diseases; Inflammation; Steroids; Immunosuppressive Agents; MRI;

Subject

Medicine and Pharmacology, Neuroscience and Neurology

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