Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Bmtret1 Gene Family and Its Potential Role in Response to BmNPV Stress in Bombyx mori

Version 1 : Received: 6 November 2023 / Approved: 6 November 2023 / Online: 6 November 2023 (14:21:46 CET)

A peer-reviewed article of this Preprint also exists.

Lin, M.; Qian, Y.; Chen, E.; Wang, M.; Ouyang, G.; Xu, Y.; Zhao, G.; Qian, H. The Bmtret1 Gene Family and Its Potential Role in Response to BmNPV Stress in Bombyx mori. Int. J. Mol. Sci. 2024, 25, 402. Lin, M.; Qian, Y.; Chen, E.; Wang, M.; Ouyang, G.; Xu, Y.; Zhao, G.; Qian, H. The Bmtret1 Gene Family and Its Potential Role in Response to BmNPV Stress in Bombyx mori. Int. J. Mol. Sci. 2024, 25, 402.

Abstract

Trehalose is a non-reducing disaccharide and participates in physiological activities such as or-gan formation, energy metabolism, and stress resistance of insects. In the present study, phylo-genetic analysis divided 21 Bmtret1 orthologs into three clades. These genes are equally distrib-uted on the nine chromosomes. Cis-elements in the promoter regions of Bmtret1s indicated the possible function of Bmtret1s in response to hormones and environmental stimulus. The qPCR analysis showed the significantly different expression levels of Bmtret1s in different tissues and organs, indicating possible functional divergence. In addition, most Bmtret1s showed disturbed expression levels in response to BmNPV stresses. Our results provide a foundation for further functional dissection of Tret1s in Bombyx mori and implicate them as potential regulators for an-tiviral responses.

Keywords

Bombyx mori; Bmtret1; BmNPV resistance; Bioinformatics analysis; Viral replication

Subject

Biology and Life Sciences, Insect Science

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