Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Scoping Review of Clinical Evidence for the Health Benefits of Culinary Doses of Herbs and Spices for Prevention and Treatment of Metabolic Syndrome

Version 1 : Received: 30 October 2023 / Approved: 31 October 2023 / Online: 31 October 2023 (04:09:55 CET)

A peer-reviewed article of this Preprint also exists.

Mackonochie, M.; Rodriguez-Mateos, A.; Mills, S.; Rolfe, V. A Scoping Review of the Clinical Evidence for the Health Benefits of Culinary Doses of Herbs and Spices for the Prevention and Treatment of Metabolic Syndrome. Nutrients 2023, 15, 4867. Mackonochie, M.; Rodriguez-Mateos, A.; Mills, S.; Rolfe, V. A Scoping Review of the Clinical Evidence for the Health Benefits of Culinary Doses of Herbs and Spices for the Prevention and Treatment of Metabolic Syndrome. Nutrients 2023, 15, 4867.

Abstract

Metabolic syndrome is a growing global health problem. Evidence suggests that diets rich in phytochemical-containing herbs and spices can contribute to reduced risk of chronic disease. This review assesses the scope of evidence supporting the use of herbs and spices in the diet for prevention or treatment of metabolic syndrome and associated health conditions. A search of PubMed and Scopus databases was carried out to assess the available clinical or cohort evidence for culinary doses of commonly used herbs and spices. Trials that were measuring health factors related to metabolic disorders or the health of individuals with metabolic syndrome or associated diseases were included. Out of a total of 1742 papers identified, there were 146 relevant studies on black pepper, chilli, cardamom, cinnamon, coriander, cumin, fennel, fenugreek, garlic, ginger, Nigella seed, rosemary, sage and turmeric. No relevant research was found for cloves, mint, oregano, parsley or thyme. Cinnamon, fenugreek and ginger were the herbs/spices with the most published trials on them and showed promise for glycaemic control. Cardamom appears to have potential to reduce inflammatory markers, and cinnamon, ginger and turmeric for blood lipids. Patients with type 2 diabetes were the population most likely to be included in studies, but the preventative benefits of herbs/spices in healthy populations were also investigated, particularly for chilli, ginger and cinnamon. There is evidence for the beneficial effect of culinary doses of many common herbs/spices in the prevention and treatment of metabolic syndrome and associated disorders.

Keywords

diabetes; herbs and spices; metabolic syndrome; nutrition; phytochemicals; preventative health

Subject

Medicine and Pharmacology, Dietetics and Nutrition

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