Ibrahim, T.; Chiang, L.; Wimala, C.; Yusoff, M.A.; Srinivasan, L.; Yuen, P.L.; Allen Jr, J.C.; Chandran, S.; Rajadurai, V.S. Outcome of Nurse versus Physician-Administered Saline Enema for Meconium Obstruction of Prematurity in Very Low Birth Weight Infants. Preprints2023, 2023101092. https://doi.org/10.20944/preprints202310.1092.v1
APA Style
Ibrahim, T., Chiang, L., Wimala, C., Yusoff, M.A., Srinivasan, L., Yuen, P.L., Allen Jr, J.C., Chandran, S., & Rajadurai, V.S. (2023). Outcome of Nurse versus Physician-Administered Saline Enema for Meconium Obstruction of Prematurity in Very Low Birth Weight Infants. Preprints. https://doi.org/10.20944/preprints202310.1092.v1
Chicago/Turabian Style
Ibrahim, T., Suresh Chandran and Victor Samuel Rajadurai. 2023 "Outcome of Nurse versus Physician-Administered Saline Enema for Meconium Obstruction of Prematurity in Very Low Birth Weight Infants" Preprints. https://doi.org/10.20944/preprints202310.1092.v1
Abstract
This randomized control trial aims to test the hypothesis that twice-daily nurse-administered saline enema(SE) is comparable to physician-administrated SE in very low birth weight infants (VLBW) with meconium obstruction of prematurity (MOP). MOP is defined as no bowel opening for 48 h, and treatment failure is defined as the need for additional intervention and safety. Twice-daily SE was administered by accredited nurses, surgeons/neonatologists using standardized protocols. The outcomes were comparability of nurse to physician-administered SE in terms of frequency of administration, catheter insertion length and volume of enema, daily maximum meconium output, and treatment failure, defined as the need for additional intervention. Safety outcomes were evaluated. Twenty-eight infants were managed with SE. 389 SE were administered, 96 and 293 in 750-999g and 1000-1500g birth weight groups, respectively. Nurses administered 72.9% and 81.5% of SE in 750-999g and 1000-1500g birth weight groups, respectively. Physicians performed the rest of the SE. Daily meconium output was comparable in nurse and physician-administered SE in both groups. There were no treatment failures or adverse events in both SE group. SE administered by nurses was found to be comparable in terms of safety, efficacy, and frequency of administration to that of physician-administered SE.
Medicine and Pharmacology, Pediatrics, Perinatology and Child Health
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
