Exploring Circulating Long Non-Coding RNAs in Mild Cognitive Impairment Patients’ Blood

Bruna De Felice; Cinzia Coppola; Simona Bonavita; Elisabetta Signoriello; Concetta Montanino; Federica Farinella

doi:10.20944/preprints202310.0478.v1

A peer-reviewed article of this Preprint also exists.

De Felice, B.; Coppola, C.; Bonavita, S.; Signoriello, E.; Montanino, C.; Farinella, F. Exploring Circulating Long Non-Coding RNAs in Mild Cognitive Impairment Patients’ Blood. Biomedicines 2023, 11, 2963. De Felice, B.; Coppola, C.; Bonavita, S.; Signoriello, E.; Montanino, C.; Farinella, F. Exploring Circulating Long Non-Coding RNAs in Mild Cognitive Impairment Patients’ Blood. Biomedicines 2023, 11, 2963.

Abstract

miRNA regulatory axes in blood of MCI patients, which includes lncRNA-SNHG16, lncRNA-H19 and lncRNA-NEAT1. Microarray investigations have demonstrated modifications in the expression of long non-coding RNAs (lncRNA) in blood of patients with MCI compared with control samples. This is the first study to explore lncRNA profiles in Mild Cognitive Impairment blood. Our study proposes RNAs targets involved in molecular pathways connected to the pathogenesis of MCI.

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Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Exploring Circulating Long Non-Coding RNAs in Mild Cognitive Impairment Patients’ Blood

Abstract

Keywords

Subject

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