Version 1
: Received: 30 September 2023 / Approved: 30 September 2023 / Online: 1 October 2023 (10:16:18 CEST)
How to cite:
Tachibana, M.; Hamayasu, H.; Nakagawa, H.; Nozawa, H.; Fukuzawa, S. A Simple Cyst of the Testis was Found Incidentally during Castration for Prostatic Cancer. Preprints2023, 2023100004. https://doi.org/10.20944/preprints202310.0004.v1
Tachibana, M.; Hamayasu, H.; Nakagawa, H.; Nozawa, H.; Fukuzawa, S. A Simple Cyst of the Testis was Found Incidentally during Castration for Prostatic Cancer. Preprints 2023, 2023100004. https://doi.org/10.20944/preprints202310.0004.v1
Tachibana, M.; Hamayasu, H.; Nakagawa, H.; Nozawa, H.; Fukuzawa, S. A Simple Cyst of the Testis was Found Incidentally during Castration for Prostatic Cancer. Preprints2023, 2023100004. https://doi.org/10.20944/preprints202310.0004.v1
APA Style
Tachibana, M., Hamayasu, H., Nakagawa, H., Nozawa, H., & Fukuzawa, S. (2023). A Simple Cyst of the Testis was Found Incidentally during Castration for Prostatic Cancer. Preprints. https://doi.org/10.20944/preprints202310.0004.v1
Chicago/Turabian Style
Tachibana, M., Hayato Nozawa and Shigeki Fukuzawa. 2023 "A Simple Cyst of the Testis was Found Incidentally during Castration for Prostatic Cancer" Preprints. https://doi.org/10.20944/preprints202310.0004.v1
Abstract
Simple cysts (SCs) within the testes are rare in adults. The testicular SC lining comprises mesothelial cells. This report presents a case involving the accidental discovery of a castration-worthy SC in the right testis of a Japanese man in his 90s who was diagnosed with prostatic adenocarcinoma. Microscopic analysis revealed that the cystic wall was covered with flat to cuboidal mesothelial cells. Immunohistochemistry demonstrated mesothelial cell positivity for calretinin, Wilms tumor 1 (WT-1), Hector Battifora mesothelial epitope-1 (HBME-1), and cyclin-dependent kinase inhibitor p16 (p16INK4a). Notably, no human papillomavirus (HPV) in situ hybridization was detected. This report outlines an exceptionally rare instance of a simple cyst within the testis, suggesting the possibility of its origin from ectopic rete testis epithelium. This marks the inaugural documentation in the English literature of an SC within the testis found incidentally during castration for prostatic cancer.
Keywords
simple cyst of the testis; mesothelium; ectopic rete testis; prostatic cancer; castration; case report
Subject
Medicine and Pharmacology, Pathology and Pathobiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
