Politeo, O.; Cajic, I.; Simic, A.; Ruscic, M.; Bektasevic, M. Comparative Study of Chemical Composition and Cholinesterase Inhibition Potential of Essential Oils Isolated from Artemisia Plants from Croatia. Separations2023, 10, 546.
Politeo, O.; Cajic, I.; Simic, A.; Ruscic, M.; Bektasevic, M. Comparative Study of Chemical Composition and Cholinesterase Inhibition Potential of Essential Oils Isolated from Artemisia Plants from Croatia. Separations 2023, 10, 546.
Politeo, O.; Cajic, I.; Simic, A.; Ruscic, M.; Bektasevic, M. Comparative Study of Chemical Composition and Cholinesterase Inhibition Potential of Essential Oils Isolated from Artemisia Plants from Croatia. Separations2023, 10, 546.
Politeo, O.; Cajic, I.; Simic, A.; Ruscic, M.; Bektasevic, M. Comparative Study of Chemical Composition and Cholinesterase Inhibition Potential of Essential Oils Isolated from Artemisia Plants from Croatia. Separations 2023, 10, 546.
Abstract
The essential oil (EO) of Artemisia plants contains a large number of bioactive compounds that are widely used. The aim of this study was to analyse the chemical composition of EOs of six Arte-misia plants collected in Croatia and to test their cholinesterase inhibitory potential. GC-MS analysis of EO of A. absinthium showed that the dominant compounds are cis-sabinyl acetate and cis-epoxy-ocimene; in EO of A. abrotanum it is borneol; in EO of A. annua it is artemisia ketone, camphor, and 1,8-cineole; in EO of A. arborescens it is camphor and chamazulene; in EO of A. verlotiorum it is cis-thujone, 1,8-cineole, and trans-thujone; in EO of A. vulgaris, it is trans-thujone and trans-epoxy-ocimene. EO of the five studied Artemisia species from Croatia is rich in mono-terpenoid compounds (1,8-cineole, artemisia ketone, cis-thujone, trans-thujone, cis-epoxy-ocimene, camphor, borneol, and cis-sabinyl acetate). EO of A. arborescens is also rich in chamazulene. The results also showed that the tested EOs have moderate cholinesterase inhibi-tion potential, especially the EOs of A. annua, A. vulgaris, and A. abrotanum. This is the first anal-ysis of the chemical composition of the EOs of four Artemisia plants and the first analysis of cho-linesterase potential for plants collected in Croatia.
Keywords
Artemisia; essential oil; GC-MS; AChE; BChE
Subject
Biology and Life Sciences, Life Sciences
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
