Phytochemical Screening of Genus Primula Species Growing in Georgia and Study of Their Antioxidant and Anti-inflammatory Potentials

Nino Sukhishvili; Thierry Franck; Ange Mouithys-Mickalad; Michel Frédérich; Karen Mulkijanyan; Charlotte Sandersen; Didier Serteyn; Lasha Mskhiladze

doi:10.20944/preprints202309.2066.v1

How to cite: Sukhishvili, N.; Franck, T.; Mouithys-Mickalad, A.; Frédérich, M.; Mulkijanyan, K.; Sandersen, C.; Serteyn, D.; Mskhiladze, L. Phytochemical Screening of Genus Primula Species Growing in Georgia and Study of Their Antioxidant and Anti-inflammatory Potentials. Preprints 2023, 2023092066. https://doi.org/10.20944/preprints202309.2066.v1 Sukhishvili, N.; Franck, T.; Mouithys-Mickalad, A.; Frédérich, M.; Mulkijanyan, K.; Sandersen, C.; Serteyn, D.; Mskhiladze, L. Phytochemical Screening of Genus Primula Species Growing in Georgia and Study of Their Antioxidant and Anti-inflammatory Potentials. Preprints 2023, 2023092066. https://doi.org/10.20944/preprints202309.2066.v1

Abstract

The goal of this article was to evaluate the antioxidant and anti-inflammatory like activities of three species from genus Primula L. growing in Georgia: Primula macrocalyx, Primula woronowii and Primula saguramica . First, fractions containing shoot and root parts were air-dried, grinded and extracted by 80% ethanol followed by condensation and freeze-drying. Second, further chromatographic separations were done on Diaion HP-20 with the following solvents: H2O, methanol (50% and 100 %) and ethylacetate 100% to obtain the expected fractions.

Keywords

Primula macrocalyx; Primula woronowii; Primula saguramica; Extraction; Stoichiometric Anticatalytic; Antioxidant; ABTS; DPPH; Neutrophils; Myeloperoxidase; Reactive oxygen species

Subject

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Phytochemical Screening of Genus Primula Species Growing in Georgia and Study of Their Antioxidant and Anti-inflammatory Potentials

Abstract

Keywords

Subject

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