Preprint Communication Version 1 Preserved in Portico This version is not peer-reviewed

Influence of Implant Base Material on Secondary Bone Healing: An In-Silico Study

Version 1 : Received: 25 September 2023 / Approved: 25 September 2023 / Online: 26 September 2023 (10:15:27 CEST)

How to cite: Nayak, G.S.; Roland, M.; Wiese, B.; Hort, N.; Diebels, S. Influence of Implant Base Material on Secondary Bone Healing: An In-Silico Study. Preprints 2023, 2023091750. https://doi.org/10.20944/preprints202309.1750.v1 Nayak, G.S.; Roland, M.; Wiese, B.; Hort, N.; Diebels, S. Influence of Implant Base Material on Secondary Bone Healing: An In-Silico Study. Preprints 2023, 2023091750. https://doi.org/10.20944/preprints202309.1750.v1

Abstract

The type of implant at the fracture site has effects not only from biological perspective but also from mechanical perspective in fracture healing. Biodegradable implants such as magnesium (Mg) based alloys have shown faster secondary bone healing properties as compared to bioinert implants such as titanium (Ti). The general reasoning behind this is the benefit of Mg from biocompatibility perspectives. We study the effect of Ti and Mg as base materials for implants with their different mechanical properties. The focus of our work is on the displacements at the fracture site of the tibia and their influence on the stimulus for bone healing. We have found that in comparison to Ti, Mg implants have minimal stress shielding problem, only which led to better mechanical stimulus at the fracture site.

Keywords

Bone remodelling; Mg implants; In-silico study; stress-shielding

Subject

Chemistry and Materials Science, Biomaterials

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