Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Percutaneous Deep Venous Arterialization for Limb Salvage of No Option Patients with Chronic Limb-Threatening Ischemia

Version 1 : Received: 25 September 2023 / Approved: 25 September 2023 / Online: 26 September 2023 (04:44:37 CEST)

A peer-reviewed article of this Preprint also exists.

Spiliopoulos, S.; Davoutis, E.; Arkoudis, N.-A.; Sritharan, K.; Lechareas, S. Percutaneous Deep Venous Arterialization for Limb Salvage in No Option Patients with Chronic Limb-Threatening Ischemia. J. Clin. Med. 2023, 12, 7324. Spiliopoulos, S.; Davoutis, E.; Arkoudis, N.-A.; Sritharan, K.; Lechareas, S. Percutaneous Deep Venous Arterialization for Limb Salvage in No Option Patients with Chronic Limb-Threatening Ischemia. J. Clin. Med. 2023, 12, 7324.

Abstract

Endovascular techniques are currently considered as a first line treatment options for lower limb chronic limb-threatening ischemia (CLTI), defined by the presence of ischemic rest pain and severe tissue loss such as ulcers or gangrene. Although the technical success rate of endovascular revascularization is high, in specific patients with advanced infrapopliteal disease and absence of run-off tibial vessels ("desert foot"), the chance of successful revascularization is minimal. In order to avoid primary amputation several treatment option are currently being investigated, including different strategies such as gene therapy or venous arterialization techniques. This review focuses on the percutaneous deep venous arterialization technique, recently introduced in everyday clinical practice, as a promising, minimally invasive treatment option for limb salvage in CLTI patients presenting with “desert foot”.

Keywords

chronic limb-threatening ischemia; peripheral arterial disease; endovascular treatment; tibial vessels; percutaneous deep venous arterialization

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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