Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Synthesis of Omeprazole@AgNPs and Omeprazole Sulfide@AgNPs and Considering Their Antibacterial Properties

Version 1 : Received: 16 September 2023 / Approved: 18 September 2023 / Online: 19 September 2023 (15:28:46 CEST)

How to cite: Sharifzadeh, B.; Mahmoodi, N. O.; Ravanan, A. Synthesis of Omeprazole@AgNPs and Omeprazole Sulfide@AgNPs and Considering Their Antibacterial Properties. Preprints 2023, 2023091246. https://doi.org/10.20944/preprints202309.1246.v1 Sharifzadeh, B.; Mahmoodi, N. O.; Ravanan, A. Synthesis of Omeprazole@AgNPs and Omeprazole Sulfide@AgNPs and Considering Their Antibacterial Properties. Preprints 2023, 2023091246. https://doi.org/10.20944/preprints202309.1246.v1

Abstract

At this time, nanoparticles used to been considered for various biomedical applications due to their particular properties[1, 2]. It is already known that one of the major advances in the relative application of nanoparticles is the recognition of the steric stabilization which can increase the particle stability in the biological environment and provide the opportunities of the application of nanoparticles in the development of drug delivery systems (DDSs) for achieving drug targeting and controlled drug release. Nano crystalline silver particles (AgNPs) have major applications in biomolecular recognition of highly sensitive, anti-microbial treatment, catalysis and manufacture sensors [3-7]. The NPs for various applications medical like image quality, medicine, tissue, magnetic resonance imaging (MRI) of targeting tissues and cells styles. This is particularly the case of AgNPs significantly encompasses the whole a wide range of industrial and medical applications. In this study, we have been synthesized incorporated omeprazole and omeprazole sulfide drugs with AgNPs and the results was investigated with TEM, FT-IR, DRS and XRD. The particle size has been seen in imaging TEM about 80 nm. Moreover either Omeprazole@AgNPs or omeprazole sulfide@AgNPs are able to excrete bacteria. In this study, the antibacterial properties of drugs with silver nanoparticles also increased.

Keywords

DDSs; Metal Nanoparticle; Antibacterial; Omeprazole; Omeprazole sulfide

Subject

Chemistry and Materials Science, Organic Chemistry

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