Kurklu, H.A.; Tan, T.S.; Ozyuncu, N.; Baskovski, E.; Ozdol, C. Atherogenic Index of Plasma Predicts Obstructive Coronary Artery Disease in Patients with Stable Angina Pectoris. Diagnostics2023, 13, 3249.
Kurklu, H.A.; Tan, T.S.; Ozyuncu, N.; Baskovski, E.; Ozdol, C. Atherogenic Index of Plasma Predicts Obstructive Coronary Artery Disease in Patients with Stable Angina Pectoris. Diagnostics 2023, 13, 3249.
Kurklu, H.A.; Tan, T.S.; Ozyuncu, N.; Baskovski, E.; Ozdol, C. Atherogenic Index of Plasma Predicts Obstructive Coronary Artery Disease in Patients with Stable Angina Pectoris. Diagnostics2023, 13, 3249.
Kurklu, H.A.; Tan, T.S.; Ozyuncu, N.; Baskovski, E.; Ozdol, C. Atherogenic Index of Plasma Predicts Obstructive Coronary Artery Disease in Patients with Stable Angina Pectoris. Diagnostics 2023, 13, 3249.
Abstract
Aims: Chronic coronary syndrome is associated with several risk factors, such as dyslipidemia and hypertension. AIP has been demonstrated to be a biochemical risk factor for coronary artery disease (CAD). This study aimed to determine whether AIP is an effective parameter for estimating obstructive CAD.
Methods and Results: A total of 345 patients (mean age 62,2±10,3; 63% male) who underwent coronary angiography were included in this study. Obstructive CAD is defined as having one or more vessels with a stenosis of≥50%. Depending on the presence of obstructive CAD, all patients were divided into two groups.
The AIP was significantly higher in the obstructive coronary artery group (AIP; 0,49±0,26 vs. 0,58±0,27, p=0,002). In univariate analysis, AIP was significantly associated with obstructive coronary artery disease [OD:3,74 (CI95% 1,62-8,64), P=0,020]. The AIP was further adjusted for confounding risk factors in three multivariate analysis models. Therefore, all three models showed a significant association. According to ROC analysis, 0.49 is the cut-off value for AIP, and a value above 0.49 indicates 50% coronary artery stenosis
Conclusions: AIP may be used in the assessment of cardiovascular risk in patients with stable angina pectoris, and it may also be used to estimate obstructive CAD.
Keywords
Atherogenic Index of Plasma; Coronary artery disease; Cardiovascular risk factor; Coronary artery stenosis
Subject
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
