Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

In Vitro Evaluation of Madio Pro+ Multipurpose Disinfectant Reveals Its Efficacy against Salmonella typhimurium Biofilm

Version 1 : Received: 9 September 2023 / Approved: 11 September 2023 / Online: 13 September 2023 (02:36:24 CEST)

How to cite: Yaacob, M.F.; Nur Anisah, J.; Nur Alya Athirah, K.; Man, C.A.C.; Amran, S.S. In Vitro Evaluation of Madio Pro+ Multipurpose Disinfectant Reveals Its Efficacy against Salmonella typhimurium Biofilm. Preprints 2023, 2023090774. https://doi.org/10.20944/preprints202309.0774.v1 Yaacob, M.F.; Nur Anisah, J.; Nur Alya Athirah, K.; Man, C.A.C.; Amran, S.S. In Vitro Evaluation of Madio Pro+ Multipurpose Disinfectant Reveals Its Efficacy against Salmonella typhimurium Biofilm. Preprints 2023, 2023090774. https://doi.org/10.20944/preprints202309.0774.v1

Abstract

Biofilms are complex communities of microorganisms that adhere to surfaces and develop a protective matrix. The colonization of devices in the food and health care industries by microbial biofilms poses numerous risks. Existing antimicrobial agents often fail to penetrate the biofilm matrix, allowing the pathogen to grow and persist. The objective of this study was to evaluate the impact of MADIO PRO+ multipurpose disinfectant on Salmonella Typhimurium biofilm using crystal violet assay and FTIR spectroscopy. Results demonstrated that MADIO PRO+ multipurpose disinfectant significantly (p<0.05) inhibited biomass of S. Typhimurium biofilm and altered the structure of S. Typhimurium biofilm. In conclusion, MADIO PRO+ multipurpose disinfectant offers an advantage in biofilm control strategy. This discovery could help the food and health care industries to plan better microbial intervention strategies.

Keywords

Salmonella Typhimurium; biofilm; disinfectant

Subject

Biology and Life Sciences, Immunology and Microbiology

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