Sarkar, G.; Mondal, S.; Bhattacharya, D.; Ponraj, P.; Sawhney, S.; Bala, P.; Chakraborty, D.; Sunder, J.; De, A.K. Effect of a Multi-Strain Probiotic on Growth Performance, Lipid Panel, Antioxidant Profile, and Immune Response in Andaman Local Piglets at Weaning. Fermentation2023, 9, 970.
Sarkar, G.; Mondal, S.; Bhattacharya, D.; Ponraj, P.; Sawhney, S.; Bala, P.; Chakraborty, D.; Sunder, J.; De, A.K. Effect of a Multi-Strain Probiotic on Growth Performance, Lipid Panel, Antioxidant Profile, and Immune Response in Andaman Local Piglets at Weaning. Fermentation 2023, 9, 970.
Sarkar, G.; Mondal, S.; Bhattacharya, D.; Ponraj, P.; Sawhney, S.; Bala, P.; Chakraborty, D.; Sunder, J.; De, A.K. Effect of a Multi-Strain Probiotic on Growth Performance, Lipid Panel, Antioxidant Profile, and Immune Response in Andaman Local Piglets at Weaning. Fermentation2023, 9, 970.
Sarkar, G.; Mondal, S.; Bhattacharya, D.; Ponraj, P.; Sawhney, S.; Bala, P.; Chakraborty, D.; Sunder, J.; De, A.K. Effect of a Multi-Strain Probiotic on Growth Performance, Lipid Panel, Antioxidant Profile, and Immune Response in Andaman Local Piglets at Weaning. Fermentation 2023, 9, 970.
Abstract
The study investigated the effect of a multi-strain probiotic compound containing Bacillus coagulans, Enterococcus faecalis, Clostridium butyricum and Bacillus mesentericus as in-feed zinc oxide (ZnO) alterna-tive on growth performance, diarrhea incidence, antioxidant status, lipid profile, stress and immunity in weaned piglets. A total of 72 piglets were randomly divided into 3 groups with four replicates of six piglets each. The details of the groups were as follows; (i) weaned control group (WC) received basal diet, (ii) weaned probiotic group (WB) received basal diet and probiotics and (iii) positive control (PC) group received basal diet with 2500 mg/kg ZnO. The experiment lasted for 28 days. Probiotic supple-mentation improved growth performance and reduced diarrhea rate. Probiotics supplementation im-proved lipid profile; significantly lower levels of total cholesterol and low-density lipoprotein cholesterol and higher level of high-density lipoprotein cholesterol in WB group as compared to those of the control group (WC) were recorded. Probiotic supplementation stimulated antioxidant defense system by in-creasing total antioxidant capacity and decreasing lipid peroxidation. Probiotic supplementation down-regulated the stress biomarkers like serum cortisol and serum heat shock proteins. WB group showed higher serum levels of IgG and IgM throughout the study period and higher IgA at day 28 as compared to WC. These data suggest that supplementation of the probiotic minimizes the weaning stress, thereby improves the growth performance, lipid profile, antioxidant status and systemic as well as mucosal immunity. Therefore, the multi-strain probiotic compound may be used to replace ZnO in weaned piglets.
Biology and Life Sciences, Animal Science, Veterinary Science and Zoology
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