Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Management of Coronary Artery Disease in TAVR Patients

Version 1 : Received: 8 September 2023 / Approved: 11 September 2023 / Online: 11 September 2023 (11:32:34 CEST)

A peer-reviewed article of this Preprint also exists.

Faroux, L.; Villecourt, A.; Metz, D. The Management of Coronary Artery Disease in TAVR Patients. J. Clin. Med. 2023, 12, 7126. Faroux, L.; Villecourt, A.; Metz, D. The Management of Coronary Artery Disease in TAVR Patients. J. Clin. Med. 2023, 12, 7126.

Abstract

About half of the transcatheter aortic valve replacement (TAVR) recipients exhibit some degree of coronary artery disease (CAD), and controversial results have been reported regarding the impact of the presence and severity of CAD on clinical outcomes post-TAVR. In addition to coronary angiography, promising data has been recently reported on the use of both cardiac computed tomography angiography and the functional invasive assessment of coronary lesions whether by FFR or iFR in the work-up pre-TAVR. Despite mitigated available data, percutaneous revascularization of significant coronary lesions has been the routine strategy in TAVR candidates with CAD. Also, scarce data exists on the incidence, characteristics and management of coronary events post-TAVR, and increasing interest exist on potential coronary access challenges in patients requiring coronary angiography/intervention post-TAVR. This review provides an updated overview of the knowledge of CAD in TAVR recipients, focusing on its prevalence, clinical impact, pre- and post-procedural evaluation and management.

Keywords

coronary artery disease; TAVR; fractional flow reserve; coronary computed tomography angiography

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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