Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Medication Overuse Headache among Children - The Contri-bution of Migraine and TTH

Version 1 : Received: 27 August 2023 / Approved: 28 August 2023 / Online: 29 August 2023 (03:38:02 CEST)

A peer-reviewed article of this Preprint also exists.

Genizi, J.; Shnaider, M.; Yaniv, L.; Kerem, N.C.; Nathan, K.; Chistyakov, I. Medication Overuse Headaches among Children—The Contribution of Migraine and TTH. Life 2023, 13, 1902. Genizi, J.; Shnaider, M.; Yaniv, L.; Kerem, N.C.; Nathan, K.; Chistyakov, I. Medication Overuse Headaches among Children—The Contribution of Migraine and TTH. Life 2023, 13, 1902.

Abstract

Abstract: Medication overuse headaches is a frequent phenomenon observed in individuals suf-fering from chronic headaches. It arises due to the excessive consumption of pain-relief medica-tions, resulting in the escalation and continuous persistence of headache symptoms. Nevertheless, the prevalence and distinctive characteristics of medication overuse headaches in the pediatric population have not been comprehensively explored. The primary objective of this research is to delineate the features of medication overuse headaches in children, particularly emphasizing the investigation of its epidemiology and the diagnostic patterns for headaches. We conducted a ret-rospective study by and analyzed the medical records of children and adolescents who were evaluated at outpatient pediatric headache clinic at the Bnai Zion medical center for headache during the period spanning 2007 to 2017. Our study encompassed a cohort of 1008 patients expe-riencing headaches. Among these participants, 268 individuals (26.6%) were diagnosed with mi-graine, 250 (24.8%) exhibited tension-type headaches (TTH), and 490 (48.6%) were classified as having undifferentiated headaches. Out of the whole group, 65 had chronic headaches: 35 (54%) with migraine, 20 (30%) with tension-type headaches (TTH), and 10 (15%) with undifferentiated headache of childhood, with the majority (73%) being female.In summary, medication overuse headaches are a prevalent issue among children grappling with chronic headaches. Intriguingly, they appear to be more pronounced within the tension-type headache (TTH) group compared to migraine sufferers, and exhibit a higher prevalence among females. This study underscores the significance of early detection and careful management of medication overuse headaches in pedi-atric cases, shedding light on its distinct characteristics in the realm of childhood headache disor-ders. Further research is warranted to elucidate the underlying factors contributing to the ob-served gender disparity and the distinct prevalence rates among different headache subtypes.

Keywords

Medication Overuse Headache; Migraine; TTH; Children

Subject

Medicine and Pharmacology, Pediatrics, Perinatology and Child Health

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