Version 1
: Received: 15 August 2023 / Approved: 16 August 2023 / Online: 16 August 2023 (10:48:38 CEST)
How to cite:
Shiozawa, K.; Murakami, T.; Matsui, T.; Ito, K.; Watanabe, M. Intra-Arterial Contrast-Enhanced Ultrasonography Using Sonazoid for Hepatocellular Carcinoma: Case Reports. Preprints2023, 2023081196. https://doi.org/10.20944/preprints202308.1196.v1
Shiozawa, K.; Murakami, T.; Matsui, T.; Ito, K.; Watanabe, M. Intra-Arterial Contrast-Enhanced Ultrasonography Using Sonazoid for Hepatocellular Carcinoma: Case Reports. Preprints 2023, 2023081196. https://doi.org/10.20944/preprints202308.1196.v1
Shiozawa, K.; Murakami, T.; Matsui, T.; Ito, K.; Watanabe, M. Intra-Arterial Contrast-Enhanced Ultrasonography Using Sonazoid for Hepatocellular Carcinoma: Case Reports. Preprints2023, 2023081196. https://doi.org/10.20944/preprints202308.1196.v1
APA Style
Shiozawa, K., Murakami, T., Matsui, T., Ito, K., & Watanabe, M. (2023). Intra-Arterial Contrast-Enhanced Ultrasonography Using Sonazoid for Hepatocellular Carcinoma: Case Reports. Preprints. https://doi.org/10.20944/preprints202308.1196.v1
Chicago/Turabian Style
Shiozawa, K., Ken Ito and Manabu Watanabe. 2023 "Intra-Arterial Contrast-Enhanced Ultrasonography Using Sonazoid for Hepatocellular Carcinoma: Case Reports" Preprints. https://doi.org/10.20944/preprints202308.1196.v1
Abstract
Contrast-enhanced ultrasonography (CEUS) is useful for evaluation of the hemodynamics of hepatic tumors and surrounding he-patic parenchyma in real time. CEUS with intravenous contrast administration is well established for evaluation of hepatocellular carcinoma (HCC). On the other hand, intra-arterial (transcatheter) CEUS (IAUS) is an emerging technique that allows more selective evaluation of the arterial supply to the tumor. IAUS was performed by administration of Sonazoid® through the microcatheter and imaging of the area of the target lesion with a dedicated, contrast-specific technique. Sonazoid® (0.5 ml diluted with 49.5 ml of distilled water) was used as the contrast medium in IAUS. The diluted Sonazoid® was introduced into the feeding artery by in-termittent injection of 0.3-1.0 ml through a microcatheter placed in the artery and flushing with saline at the same flow rate. We report the three cases in which IAUS was useful in transarterial chemoembolization (TACE) for HCC. Two cases were performed TACE for hepatic metastasis. In any cases, plain computed tomography (CT) after TACE showed accumulation of Lipiodol® only in the metastases. One case was suspected having HCC rupture and urgent abdominal angiography was performed. IAUS was performed frequently to reduce the amount of iodinated contrast agent as much as possible because of renal failure. Concomitant use of IAUS enabled reduction of the amount of contrast agent.
Medicine and Pharmacology, Gastroenterology and Hepatology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
