R406W Mutant Tau Protein Conjugated with GFP Aggregates in Cells and Phorbol 12-Myristate 13-Acetate Inhibits Mutant Tau Aggregation and Promotes Neurite Outgrowth in Human Cell Culture Model of Neurodegenerative Diseases

Yasuko Tokunaga; Ayaka Osugi; Ken-Ichiro Otsuyama; Takeshi Honda; Naoki Hayashida

doi:10.20944/preprints202308.0889.v1

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R406W Mutant Tau Protein Conjugated with GFP Aggregates in Cells and Phorbol 12-Myristate 13-Acetate Inhibits Mutant Tau Aggregation and Promotes Neurite Outgrowth in Human Cell Culture Model of Neurodegenerative Diseases

This version is not peer-reviewed.

Yasuko Tokunaga,Ayaka Osugi,

Ken-Ichiro Otsuyama,

Takeshi Honda,

Naoki Hayashida^*

Yasuko Tokunaga,Ayaka Osugi,

Ken-Ichiro Otsuyama,

Takeshi Honda,

Naoki Hayashida^*

This version is not peer-reviewed.

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Submitted:

10 August 2023

Posted:

11 August 2023

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Abstract

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Subject:

Medicine and Pharmacology - Neuroscience and Neurology

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Copyright: This open access article is published under a Creative Commons CC BY 4.0 license, which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.

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R406W Mutant Tau Protein Conjugated with GFP Aggregates in Cells and Phorbol 12-Myristate 13-Acetate Inhibits Mutant Tau Aggregation and Promotes Neurite Outgrowth in Human Cell Culture Model of Neurodegenerative Diseases

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