Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Can BPA Analogs Affect Cellular and Biochemical Responses in the Microalga Phaeodactylum tricornutum Bohlin?

Version 1 : Received: 7 August 2023 / Approved: 8 August 2023 / Online: 9 August 2023 (03:11:39 CEST)

A peer-reviewed article of this Preprint also exists.

Fabrello, J.; Ciscato, M.; Moschin, E.; Vecchia, F.D.; Moro, I.; Matozzo, V. Can BPA Analogs Affect Cellular and Biochemical Responses in the Microalga Phaeodactylum tricornutum Bohlin? J. Xenobiot. 2023, 13, 479-491. Fabrello, J.; Ciscato, M.; Moschin, E.; Vecchia, F.D.; Moro, I.; Matozzo, V. Can BPA Analogs Affect Cellular and Biochemical Responses in the Microalga Phaeodactylum tricornutum Bohlin? J. Xenobiot. 2023, 13, 479-491.

Abstract

Bisphenol A analogs (BPA analogs) are emerging contaminants with a rising production caused by the replacement of BPA with these compounds. The increased production of BPA analogs is leading to an increased release into various ecosystems, including sea. The aim of this study was to evaluate the biological effects of BPA analogs on a primary producer, the diatom Phaeodactylum tricornutum Bohlin. Three different BPA analogs (BPAF, BPF, and BPS) and their mixture were tested at the environmental relevant concentration of 300 ng/L. Growth curve, cell size and several biomarkers of oxidative stress and oxidative damage were measured. Our results indicated that the tested compounds caused alteration of the growth and induced oxidative stress altering many antioxidant enzymes. However, no oxidative damages were observed.

Keywords

bisphenol analogs; BPA; microalgae; biomarkers; Phaeodactylum tricornutum

Subject

Environmental and Earth Sciences, Pollution

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