preprints.org > medicine and pharmacology > neuroscience and neurology > doi: 10.20944/preprints202308.0104.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 31 July 2023 / Approved: 1 August 2023 / Online: 2 August 2023 (10:08:37 CEST)

Chiari malformation type 1 (CM1) includes a series of congenital anomalies that share ectopia of the cerebellar tonsils below the foramen magnum, in some cases associated with syringomyelia or hydrocephalus. CM1 can cause dysfunction of the brainstem, spinal cord, and cranial nerves. This functional alteration of the nervous system can be detected by various modalities of neurophysiological tests, such as brainstem auditory evoked potentials, somatosensory evoked potentials, motor evoked potentials, electromyography and nerve conduction studies of the cranial nerves and spinal roots, as well as brainstem reflexes. The main goal of this study is to review the findings of multimodal neurophysiological examinations in published studies of patients with CM1 and their indication in the diagnosis, treatment, and follow-up of these patients, as well as their utility in intraoperative monitoring.

blink reflex; brainstem auditory evoked potentials; brainstem reflexes; Chiari type 1 malformation; electromyography; evoked potentials; intraoperative monitoring; motor evoked potentials; somatosensory evoked potentials; syringomyelia.

Medicine and Pharmacology, Neuroscience and Neurology

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