Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Electrical Manipulation, Characterization and Application of Single Cell

Version 1 : Received: 31 July 2023 / Approved: 1 August 2023 / Online: 1 August 2023 (10:50:09 CEST)

A peer-reviewed article of this Preprint also exists.

Zhu, W.; Wang, J.; Luo, H.; Luo, B.; Li, X.; Liu, S.; Li, C. Electrical Characterization and Analysis of Single Cells and Related Applications. Biosensors 2023, 13, 907. Zhu, W.; Wang, J.; Luo, H.; Luo, B.; Li, X.; Liu, S.; Li, C. Electrical Characterization and Analysis of Single Cells and Related Applications. Biosensors 2023, 13, 907.

Abstract

Biological parameters extracted from electrical signals from various body parts have been used for many years to analyze the human body and its behavior. In addition, electrical signals from cancer cell lines, normal cells, and viruses, among others, have been widely used for the detection of various diseases. Single-cell parameters such as cell and cytoplasmic conductivity, relaxation frequency, and membrane capacitance are important. There are many techniques available to characterize biomaterials, such as scanning tunneling microscopy (STM), nanotechnology, microstrip cavity resonance measurement, dielectric impedance measurement (DEPIM), etc. This article reviews the single cell isolation and sorting techniques, summarizes the common single cell operations such as impedance flow cytometry, cell electrical impedance, electrical impedance sensing, and summarizes the current single cell analysis techniques and their applications.

Keywords

single-cell analysis; electrical manipulation; single-cell application

Subject

Engineering, Bioengineering

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