Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Probiotics Change the Microbiota: From the Lab to the Bedside

Version 1 : Received: 14 July 2023 / Approved: 14 July 2023 / Online: 14 July 2023 (16:49:09 CEST)

How to cite: Patil, A.; Singh, N. Probiotics Change the Microbiota: From the Lab to the Bedside. Preprints 2023, 2023071028. https://doi.org/10.20944/preprints202307.1028.v1 Patil, A.; Singh, N. Probiotics Change the Microbiota: From the Lab to the Bedside. Preprints 2023, 2023071028. https://doi.org/10.20944/preprints202307.1028.v1

Abstract

Probiotics have become a potential way to change the microbiota, which allows for more personalized ways to improve health results. This abstract gives an outline of the most important parts of personalized microbiota regulation through probiotics. It focuses on effectiveness and mechanisms, clinical applications, safety and tolerability, formulations and delivery methods, and customized approaches. Many studies have looked into how and why probiotics change the microbiome. These studies show that probiotics can change the makeup and function of microbial communities. Probiotics have been shown to help treat a number of health problems, such as digestive problems, immune system problems, metabolic problems, and mental health problems. It is important for the success of probiotics to find out if they are safe and can be tolerated. Studies have shown that probiotics are usually safe for most people, but there are some things that need to be taken into account to make sure they are safe, especially for people who are weak. Formulations and transport methods are very important for making sure that probiotics are alive, stable, and delivered to the right places in the GI tract. Probiotic strains work better in the gut because of improvements in how probiotic preparation technologies protect and control the release of probiotic strains. Personalized methods take into account how each person's microbiome and health are different. By using individual microbiota profiling, custom probiotic approaches can be made to address specific microbial imbalances and promote a healthier microbial environment, which could improve treatment results. Even though individual methods show promise, there are still problems, such as the need to standardize microbiota profiling techniques, figure out how to understand data, and keep track of people over time. For personalized probiotics to reach their full potential and change the way patients are cared for based on the microbiota-host relationship, more study, technological advances, and teamwork are needed. In conclusion, probiotics can be used to change your microbiome in a way that is specific to you and your health goals. By using the power of individualized microbiota profiling, personalized probiotic treatments might be able to help with certain health problems and make the microbial environment better. Putting personalized probiotics into clinical practice and changing the way patients are cared for will require more study and partnerships between different fields.

Keywords

Microbiota; probiotics; formulations; immune system

Subject

Biology and Life Sciences, Immunology and Microbiology

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