Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

A Study of Dietary Patterns of Patients with Mild Cognitive Impairment

Version 1 : Received: 10 July 2023 / Approved: 11 July 2023 / Online: 11 July 2023 (10:45:47 CEST)

A peer-reviewed article of this Preprint also exists.

Nien, S.-W.; Lin, I.-H.; Wu, H.-C.; Chen, Y.-H.; Yang, S.-C. Evaluation of Dietary Intake in Individuals with Mild Cognitive Impairment. Nutrients 2023, 15, 3694. Nien, S.-W.; Lin, I.-H.; Wu, H.-C.; Chen, Y.-H.; Yang, S.-C. Evaluation of Dietary Intake in Individuals with Mild Cognitive Impairment. Nutrients 2023, 15, 3694.

Abstract

The time when a patient has mild cognitive impairment (MCI) is an important period for delaying the onset of dementia and has been the main target of dementia prevention research in recent years. The purpose of this study was to investigate the dietary intake and dietary patterns of MCI patients in Taiwan. In total, 40 subjects were enrolled in this cross-sectional study that was conducted from July 2019 to September 2021 at Linkou Chang Gung Memorial Hospital. Results of the clinical dementia rating (CDR) and mini-mental state examination (MMSE) were obtained from medical records. Participants were divided into two groups: a healthy group (MMSE ≥ 26 points, CDR=0) and an MCI group (MMSE ≥ 26 points, CDR=0.5). Results indicated that the MCI group had significantly higher copper and lower low-fat meat intake compared to the healthy group. Furthermore, the high MIND (Mediterranean-dietary approaches to stop hypertension intervention for neurodegenerative delay) diet score represented a lower risk of MCI. After adjusting for age and gender in the multivariate regression analysis, calcium and fruit intake levels were positively associated with the MMSE. In conclusion, the prevalence of MCI was closely associated with dietary intake, such as copper and calcium, as well as dietary patterns, particularly the MIND diet.

Keywords

mild cognitive impairment; dietary intake; dietary pattern; MIND diet

Subject

Medicine and Pharmacology, Dietetics and Nutrition

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