Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Oil Pulling and Polyphenols: Treatment of Gingivitis Patients With ‘Itri Extra Virgin Olive Oil’

Version 1 : Received: 4 July 2023 / Approved: 10 July 2023 / Online: 10 July 2023 (11:29:53 CEST)

A peer-reviewed article of this Preprint also exists.

Zumbo, G.; Corridore, D.; Sciscione, S.; Stamegna, C.; Guerra, F.; Polimeni, A.; Vozza, I. Oil Pulling and Polyphenols: Treatment of Gingivitis Patients with ‘Itri Extra-Virgin Olive Oil’. J. Clin. Med. 2023, 12, 5256. Zumbo, G.; Corridore, D.; Sciscione, S.; Stamegna, C.; Guerra, F.; Polimeni, A.; Vozza, I. Oil Pulling and Polyphenols: Treatment of Gingivitis Patients with ‘Itri Extra-Virgin Olive Oil’. J. Clin. Med. 2023, 12, 5256.

Abstract

Objectives The aim of the study is to evaluate the effectiveness of extra virgin olive oil (EVO) and fruity oil for the treatment of gingivitis. Materials and Methods. A sample of 75 patients with gingivitis induced by plaque bacteria, over 18 years of age, was divided into three groups: a study group A with extra virgin olive oil, a study group B with fruity oil and a control group C. In the two study groups, Evo oil was administered as a mouthwash in patients with gingival inflammation. The protocol included a daily application of the product for 30 days, with three recalls 15 days apart. Clinical parameters of plaque formation and gingivitis - plaque index (PI), bleeding index (BI) were assessed at each recall and scored on a specific periodontal chart. The control group re-ceived no mouthwash treatment to normal daily oral hygiene procedures, and the same clinical parameters as the study group were evaluated. Data were evaluated using SPSS 27.0 software for Windows (SPSS Inc., Chica-go, IL, USA). Then, the pre- and post-treatment values of the groups were compared using the t-student test, set-ting P < 0.05 as the significance level. Results Comparison with the three groups showed that extra virgin olive oil was an adjuvant in the treatment of gingival inflammation, improving PI and BI. In group A, mean plaque index had a 48% reduction and bleeding index 64% reduction, after 30 days. In group B, the mean plaque index had a 35% reduction and a bleeding index reduction of 43%, after 30 days. Conclusion The collected data showed significant improvements in the formation of bacterial plaque and gingi-vitis. the exact mechanism of such treatment is still to be elucidated. As a result of this, further studies with a different sample of patients to those used and a comparison with other products need to be addressed to verify and demonstrate the antibacterial and anti-inflammatory effect of the components of this natural product.

Keywords

oil pulling; oral health; gingivitis; dentistry; dentistry innovations; polyphenols

Subject

Medicine and Pharmacology, Dentistry and Oral Surgery

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