Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Autoimmune Encephalitis – a variable pathology

Version 1 : Received: 5 July 2023 / Approved: 6 July 2023 / Online: 7 July 2023 (10:13:27 CEST)

A peer-reviewed article of this Preprint also exists.

Neațu, M.; Jugurt, A.; Covaliu, A.; Davidescu, E.I.; Popescu, B.O. Autoimmune Encephalitis—A Multifaceted Pathology. Biomedicines 2023, 11, 2176. Neațu, M.; Jugurt, A.; Covaliu, A.; Davidescu, E.I.; Popescu, B.O. Autoimmune Encephalitis—A Multifaceted Pathology. Biomedicines 2023, 11, 2176.

Abstract

Abstract: Autoimmune encephalitis is a complex and multifaceted pathology that involves the immune-mediated inflammation of the brain. It is characterized by the body's immune system mistakenly attacking the brain tissue, leading to a cascade of inflammatory processes. What makes autoimmune encephalitis vast is the wide range of causes, mechanisms, clinical presentations, and diagnostic challenges associated with the condition. The clinical presentations of autoimmune encephalitis are broad and can mimic other neurological disorders, making it a challenging differential diagnosis. This diverse clinical presentation can overlap with other conditions, making it crucial for healthcare professionals to maintain a high level of suspicion for autoimmune encephalitis when evaluating patients. The diagnostic challenges associated with autoimmune encephalitis further contribute to its vastness. Due to the variable nature of the condition, there is no definitive diagnostic test that can confirm autoimmune encephalitis in all cases. In this context, personalized patient management is crucial for achieving favorable outcomes. Each patient's treatment plan should be tailored to their specific clinical presentation, underlying cause, and immune response. Our objective is to raise awareness about the frequent yet under-diagnosed nature of autoimmune encephalitis by sharing five cases we encountered, along with a brief literature review.

Keywords

autoimmune encephalitis; encephalitis symptoms; diagnosis autoimmune encephalitis; treatment autoimmune encephalitis

Subject

Medicine and Pharmacology, Neuroscience and Neurology

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