PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
Development of Anthropomorphic Heterogeneous Pelvic Phantom and Its Comparison with Homogeneous Phantom in Advance Radiation Therapy: Dosimetry Analysis
Version 1
: Received: 4 July 2023 / Approved: 4 July 2023 / Online: 5 July 2023 (02:45:28 CEST)
How to cite:
Yadav, N.; Singh, M.; Mishra, S.P.; Ansari, S. Development of Anthropomorphic Heterogeneous Pelvic Phantom and Its Comparison with Homogeneous Phantom in Advance Radiation Therapy: Dosimetry Analysis. Preprints2023, 2023070242. https://doi.org/10.20944/preprints202307.0242.v1
Yadav, N.; Singh, M.; Mishra, S.P.; Ansari, S. Development of Anthropomorphic Heterogeneous Pelvic Phantom and Its Comparison with Homogeneous Phantom in Advance Radiation Therapy: Dosimetry Analysis. Preprints 2023, 2023070242. https://doi.org/10.20944/preprints202307.0242.v1
Yadav, N.; Singh, M.; Mishra, S.P.; Ansari, S. Development of Anthropomorphic Heterogeneous Pelvic Phantom and Its Comparison with Homogeneous Phantom in Advance Radiation Therapy: Dosimetry Analysis. Preprints2023, 2023070242. https://doi.org/10.20944/preprints202307.0242.v1
APA Style
Yadav, N., Singh, M., Mishra, S.P., & Ansari, S. (2023). Development of Anthropomorphic Heterogeneous Pelvic Phantom and Its Comparison with Homogeneous Phantom in Advance Radiation Therapy: Dosimetry Analysis. Preprints. https://doi.org/10.20944/preprints202307.0242.v1
Chicago/Turabian Style
Yadav, N., Surendra Prasad Mishra and Shahnawaz Ansari. 2023 "Development of Anthropomorphic Heterogeneous Pelvic Phantom and Its Comparison with Homogeneous Phantom in Advance Radiation Therapy: Dosimetry Analysis" Preprints. https://doi.org/10.20944/preprints202307.0242.v1
Abstract
Introduction: To compare the results of patient-specific absolute dosimetry using homogeneous slab phantom and anthropomorphic heterogeneous female pelvic phantom in cervical cancer patients. Materials and method: Thirty RapidArc plans already planned on treatment planning system (TPS) for cervical cancer patients were exported on both the phantoms viz. RW3 slab phantom and AHFP and dose were calculated using an anisotropic analytic algorithm (AAA). All the plans were delivered by linear accelerator (LA) and the dose for each plan was measured by a 0.6cc ion chamber. The percentage (%) variation between planned and measured doses were calculated and analyzed.Results: In the case of slab phantom, the mean percentage variations between planned and measured doses of all rapid arc QA plans were as 1.4299 and standard deviation 0.768 (t=0.00508, ρ= 0.497982) The result is not significant at p < .05. For the AHFP phantom, the mean percentage variations between planned and measured doses of all rapid arc QA plans were as 6.890 and standard deviation 2.565 (t= 3.21604, ρ= 0.001063 <0.05), the outcome is significant. Discussion: In the case of homogenous slab phantom, there is less than a 3% difference in percentage between planned and measured doses with a standard deviation of 0.7682 (t=0.00508, p= .497982. The result is not significant at p< 0.05). The deviations of planned and measured value of dose in the AHFP phantom were found as 10.67% (maximum value), 2.31% (minimum value) and 6.89% (average value) with standard deviation 2.565 (t=3.21604, p=0.001063. The result is significant at p<0.05). Also, the percentage of variation between homogeneous slab phantoms with AHFP phantom, the t-value is -11.17016. The p-value is < .00001. The result is significant at p<0.05. We can see that the outcomes differ significantly due to the influence of heterogeneous media.Conclusion: AHFP phantom results showed more dose variability than slab homogenous phantom outcomes. Therefore, patient-specific absolute dosimetry should be performed using a heterogeneous phantom that closely resembles the actual human body in terms of both density and design.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
