Version 1
: Received: 29 June 2023 / Approved: 30 June 2023 / Online: 3 July 2023 (14:22:55 CEST)
How to cite:
González, I.; Lindner, C.; Schneider, I.; Diaz, E.; Morales, M.A.; Rojas, A. The Multifaceted Actions of Polyphenols in the Management of Type-2 Diabetes Mellitus. Preprints2023, 2023070110. https://doi.org/10.20944/preprints202307.0110.v1
González, I.; Lindner, C.; Schneider, I.; Diaz, E.; Morales, M.A.; Rojas, A. The Multifaceted Actions of Polyphenols in the Management of Type-2 Diabetes Mellitus. Preprints 2023, 2023070110. https://doi.org/10.20944/preprints202307.0110.v1
González, I.; Lindner, C.; Schneider, I.; Diaz, E.; Morales, M.A.; Rojas, A. The Multifaceted Actions of Polyphenols in the Management of Type-2 Diabetes Mellitus. Preprints2023, 2023070110. https://doi.org/10.20944/preprints202307.0110.v1
APA Style
González, I., Lindner, C., Schneider, I., Diaz, E., Morales, M.A., & Rojas, A. (2023). The Multifaceted Actions of Polyphenols in the Management of Type-2 Diabetes Mellitus. Preprints. https://doi.org/10.20944/preprints202307.0110.v1
Chicago/Turabian Style
González, I., MIguel A. Morales and Armando Rojas. 2023 "The Multifaceted Actions of Polyphenols in the Management of Type-2 Diabetes Mellitus" Preprints. https://doi.org/10.20944/preprints202307.0110.v1
Abstract
Type-2 diabetes mellitus is recognized as a serious public health concern with a considerable impact on human life, long-term health expenditures, and substantial health losses.
In this context, the use of dietary polyphenols to prevent and manage Type 2 diabetes mellitus is widely documented. These dietary compounds exert their beneficial effects by several actions, including the protection of pancreatic islet β-cell, the antioxidant capacities of these molecules, their effects on insulin secretion and actions, the regulation of intestinal microbiota, and their contribution to ameliorating diabetic complications, particularly those of vascular origin.
In the present review, we intend to highlight these multifaceted actions and the molecular mechanisms by which these plant-derived secondary metabolites exert their beneficial effects on type-2 diabetes patients.
Medicine and Pharmacology, Dietetics and Nutrition
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
