Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Lateral Spread Response: Unveiling the Smoking Gun for Cured Hemifacial Spasm

Version 1 : Received: 29 June 2023 / Approved: 30 June 2023 / Online: 30 June 2023 (12:20:01 CEST)

A peer-reviewed article of this Preprint also exists.

Cho, K.R.; Park, S.K.; Park, K. Lateral Spread Response: Unveiling the Smoking Gun for Cured Hemifacial Spasm. Life 2023, 13, 1825. Cho, K.R.; Park, S.K.; Park, K. Lateral Spread Response: Unveiling the Smoking Gun for Cured Hemifacial Spasm. Life 2023, 13, 1825.

Abstract

Hemifacial spasm (HFS) is a rare disorder characterized by involuntary facial muscle contractions. The primary cause is mechanical compression of the facial nerve by nearby structures. Lateral spread response (LSR) is an abnormal muscle response observed during electromyogram (EMG) testing and is associated with HFS. Intraoperative monitoring of LSR is crucial during surgery to confirm successful decompression. Proper anesthesia and electrode positioning are important for accurate LSR monitoring. Stimulation parameters should be carefully adjusted to avoid artifacts. The disappearance of LSR during surgery is associated with short-term outcomes, but its persistence does not necessarily indicate poor long-term outcomes. LSR monitoring has both positive and negative prognostic value, and its predictive ability varies across studies. Early disappearance of LSR can occur before decompression and may indicate better clinical outcomes. Further research is needed to fully understand the implications of LSR monitoring in HFS surgery.

Keywords

Lateral spread response; abnormal muscle response; hemifacial spasm

Subject

Medicine and Pharmacology, Neuroscience and Neurology

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