Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Investigation of Renal Function in Patients with Long COVID in the Amazon Region: A Cross-Sectional Study

Version 1 : Received: 27 June 2023 / Approved: 27 June 2023 / Online: 27 June 2023 (07:20:09 CEST)

How to cite: Assis, G.M.C.C.D.; Veiga, I.G.D.; Reis, R.D.N.R.; Menezes, D.C.D.; Xavier, S.S.; Sousa, J.R.D.; Quaresma, J.A.S.; Falcão, L.F.M.; Lima, P.D.L.D. Investigation of Renal Function in Patients with Long COVID in the Amazon Region: A Cross-Sectional Study. Preprints 2023, 2023061854. https://doi.org/10.20944/preprints202306.1854.v1 Assis, G.M.C.C.D.; Veiga, I.G.D.; Reis, R.D.N.R.; Menezes, D.C.D.; Xavier, S.S.; Sousa, J.R.D.; Quaresma, J.A.S.; Falcão, L.F.M.; Lima, P.D.L.D. Investigation of Renal Function in Patients with Long COVID in the Amazon Region: A Cross-Sectional Study. Preprints 2023, 2023061854. https://doi.org/10.20944/preprints202306.1854.v1

Abstract

Long coronavirus disease 2019 (COVID-19) may occur after experiencing acute COVID-19 infec-tion with many effects on patients´ kidneys. This study aimed to evaluate the clinical and labora-tory aspects of kidney function in individuals with long COVID in the Amazon region of Brazil. This cross-sectional study selected participants from a ‘long COVID’ clinical care program. Clini-cal data and baseline demographics were obtained, and blood samples were collected to quantify kidney-related markers. Patients were evaluated after COVID-19 infection at several time points as follows: 0–3 months, 3–6 months, 6–12 months, and 12 months. Altogether, 246 patients were selected for this study, and only 79 were hospitalised (9 in the intensive care unit because of COVID-19. Of the patients, 38 were diagnosed with hypertension after COVID-19, 52 cases had to have their medications adjusted, and 83 patients presented with kidney function decline. The older age group and individuals with glycaemic alterations presented with a higher risk of devel-oping kidney dysfunction. Therefore, health professionals should monitor long-term kidney mark-ers in long COVID.

Keywords

SARS-CoV-2; COVID -19; Chronic Kidney Disease; Long COVID; Acute Kidney Injury; Amazon region; Kidney function tests

Subject

Medicine and Pharmacology, Urology and Nephrology

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