Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

New Food-Frequency Questionnaire to Estimate Vitamin K intake in a Mediterranean Population

Ezequiel Pinto
ORCID logo ,
Carla Viegas
,
Paula Ventura Martins
ORCID logo ,
Tânia Nascimento
ORCID logo ,
Leon Schurgers
ORCID logo ,
Dina Simes
* ORCID logo
Version 1 : Received: 23 June 2023 / Approved: 26 June 2023 / Online: 26 June 2023 (15:06:28 CEST)

A peer-reviewed article of this Preprint also exists.

Pinto, E.; Viegas, C.; Martins, P.V.; Nascimento, T.; Schurgers, L.; Simes, D. New Food Frequency Questionnaire to Estimate Vitamin K Intake in a Mediterranean Population. Nutrients 2023, 15, 3012. Pinto, E.; Viegas, C.; Martins, P.V.; Nascimento, T.; Schurgers, L.; Simes, D. New Food Frequency Questionnaire to Estimate Vitamin K Intake in a Mediterranean Population. Nutrients 2023, 15, 3012.

Abstract

Vitamin K is a multifunctional micronutrient essential for human health, and deficiency has been linked to multiple pathological conditions. In this study we aimed to develop and validate a new food frequency questionnaire (FFQ) to estimate total vitamin K intake, over the course of a 30-day interval, in a Portuguese, Mediterranean-based, population. We conducted a prospective study in a non-random sample of 38 healthy adult volunteers. The FFQ was designed based on a validated Portuguese FFQ used in nationally representative studies and on literature reviews, to include foods containing ≥ 5μg of vitamin K/100g and foods with a lower vitamin K content, yet commonly in-cluded in a Mediterranean diet. Vitamin K intake was estimated from 24h recalls and six days of food records. The final FFQ included 54 food items which, according to regression analyses, explains 90% of vitamin K intake. Mean differences in vitamin K intake based on food records (80±47.7 μg/day) and on FFQ (96.5±64.3 μg/day) were statistically non-significant. Further, we found a strong correlation between both methods (r= 0.7; p=0.003). Our results suggest that our new FFQ is a valid instrument to assess the last 30-days of vitamin K intake in the Portuguese Mediterranean population.

Keywords

Vitamin K; Food Frequency Questionnaire; Dietary Intake; Mediterranean Diet

Subject

Medicine and Pharmacology, Dietetics and Nutrition

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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