Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Cerebrovascular Disease in COVID-19

Version 1 : Received: 19 June 2023 / Approved: 20 June 2023 / Online: 20 June 2023 (15:13:35 CEST)

A peer-reviewed article of this Preprint also exists.

Siegler, J.E.; Dasgupta, S.; Abdalkader, M.; Penckofer, M.; Yaghi, S.; Nguyen, T.N. Cerebrovascular Disease in COVID-19. Viruses 2023, 15, 1598. Siegler, J.E.; Dasgupta, S.; Abdalkader, M.; Penckofer, M.; Yaghi, S.; Nguyen, T.N. Cerebrovascular Disease in COVID-19. Viruses 2023, 15, 1598.

Abstract

Not in the history of transmissible illnesses has there been an infection as strongly associated with acute cerebrovascular disease as the novel human coronavirus, SARS-CoV-2. While the risk of stroke has known associations with other viral infections, such as influenza and human immunodeficiency virus, the risk of ischemic and hemorrhagic stroke related to SARS-CoV-2 is unprecedented. Furthermore, the coronavirus disease 2019 (COVID-19) pandemic has so profoundly impacted psychosocial behaviors and modern medical care that we have witnessed shifts in epidemiology and have adapted our treatment practices to reduce transmission, address delayed diagnoses, and mitigate gaps in health care. In this narrative review, we summarize the history and impact of the COVID-19 pandemic on cerebrovascular disease, and lessons learned regarding the management of patients as we endure this period of human history.

Keywords

Coronavirus disease 2019; COVID-19; Stroke; Cerebral vein thrombosis; Intracranial hemorrhage; Anticoagulation; Mechanical thrombectomy; Intravenous thrombolysis

Subject

Medicine and Pharmacology, Neuroscience and Neurology

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