Diabetic Retinopathy and the Extracellular Vesicles.

Kuppamuthu Dharmalingam; Kim Ramasamy

doi:10.20944/preprints202306.0865.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 12 June 2023 / Approved: 13 June 2023 / Online: 13 June 2023 (03:08:48 CEST)

Diabetes and diabetes-induced micro and macrovascular complications are major causes of healthcare problems. The extracellular vesicles are produced by all cells from all organisms. They are shown to have properties of the producer cells and also reflect the host physiology and pathology. Since the EVs represent the cellular state they are excellent biomarkers. In this review, we will focus on the EVs produced by the Neuro Vascular Unit cells of the eye as well as the extraocular cells in the onset and progression of diabetic retinopathy. A brief account of the use of these nanovesicles in personalised medicine is also given.

Diabtetic retinoapthy; Exosomes; extracellular vesicles; precision medicine

Biology and Life Sciences, Cell and Developmental Biology

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Diabetic Retinopathy and the Extracellular Vesicles.

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