Looking for the Ideal Probiotic Healing Regime

Alexandra Menni; Moysis Moysidis; Georgios Tzikos; George Stavrou; Joulia K Tsetis; Anne D Shrewsbury; Eirini Filidou; Katerina Kotzampassi

doi:10.20944/preprints202306.0851.v1

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preprints.org > medicine and pharmacology > medicine and pharmacology > doi: 10.20944/preprints202306.0851.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Looking for the Ideal Probiotic Healing Regime

Version 1 : Received: 10 June 2023 / Approved: 12 June 2023 / Online: 12 June 2023 (14:46:07 CEST)

A peer-reviewed article of this Preprint also exists.

Menni, A.; Moysidis, M.; Tzikos, G.; Stavrou, G.; Tsetis, J.K.; Shrewsbury, A.D.; Filidou, E.; Kotzampassi, K. Looking for the Ideal Probiotic Healing Regime. Nutrients 2023, 15, 3055. Menni, A.; Moysidis, M.; Tzikos, G.; Stavrou, G.; Tsetis, J.K.; Shrewsbury, A.D.; Filidou, E.; Kotzampassi, K. Looking for the Ideal Probiotic Healing Regime. Nutrients 2023, 15, 3055.

Abstract

Wound healing is a multi-factorial response to tissue injury, aiming to restore tissue continuity. Numerous recent experimental and some clinical studies, clearly indicate that probiotics applied topically promote the wound healing process. However, the precise mechanism by which they contribute to healing is not yet clear. Each strain appears to exert a distinctive, even multi-factorial action on different phases of the healing process. Given that a multi-probiotic formula exerts better results than a single strain, the pharmaceutical industry has embarked on a race for the production of a formulation containing a combination of probiotics, capable of playing a role in all the phases of the healing process. Hence, the object of this review is to describe what is known to date of the distinctive mechanisms of each of the most studied probiotic strains in order to further facilitate research towards the development of combinations of strains and doses, covering the whole spectrum of healing. Eleven probiotic species have been analyzed, the only criterion of inclusion being a minimum of two published research articles.

Keywords

wound healing; probiotics; lactoplantibacillus plantarum; lactobacillus rhamnosus; lactobacillus acidophilus; Bifidobacterium longum; lactobacillus casei; lactobacillus reuteri; lactobacillus refmentum

Subject

Medicine and Pharmacology, Medicine and Pharmacology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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