Version 1
: Received: 9 June 2023 / Approved: 12 June 2023 / Online: 12 June 2023 (13:05:28 CEST)
How to cite:
Surpateanu, G.; Georgescu, A.-M.; Nistor, I.-D.; Lungu, N. C. Synthon Chemistry. Theoretical Study on the Formation of Glutamic Acid, Glutamine, Lysine and Arginine. Preprints2023, 2023060835. https://doi.org/10.20944/preprints202306.0835.v1
Surpateanu, G.; Georgescu, A.-M.; Nistor, I.-D.; Lungu, N. C. Synthon Chemistry. Theoretical Study on the Formation of Glutamic Acid, Glutamine, Lysine and Arginine. Preprints 2023, 2023060835. https://doi.org/10.20944/preprints202306.0835.v1
Surpateanu, G.; Georgescu, A.-M.; Nistor, I.-D.; Lungu, N. C. Synthon Chemistry. Theoretical Study on the Formation of Glutamic Acid, Glutamine, Lysine and Arginine. Preprints2023, 2023060835. https://doi.org/10.20944/preprints202306.0835.v1
APA Style
Surpateanu, G., Georgescu, A. M., Nistor, I. D., & Lungu, N. C. (2023). Synthon Chemistry. Theoretical Study on the Formation of Glutamic Acid, Glutamine, Lysine and Arginine. Preprints. https://doi.org/10.20944/preprints202306.0835.v1
Chicago/Turabian Style
Surpateanu, G., Ileana-Denisa Nistor and Neculai Catalin Lungu. 2023 "Synthon Chemistry. Theoretical Study on the Formation of Glutamic Acid, Glutamine, Lysine and Arginine" Preprints. https://doi.org/10.20944/preprints202306.0835.v1
Abstract
This paper represents a thermodynamic and chemical reactivity study regarding the possible formation of four proteinogenic amino acids: glutamic acid, glutamine, lysine and arginine, starting from three synthons: methylene, nitrene and carbon monoxide. All intermediates are specified: neutral molecules and radicals involved in the formation of these four proteinogenic amino acids. The study is based on the synthonic theory of the formation of the first proteinogenic amino acids and their corresponding polypeptides. The thermodynamic quantitative data are obtained from mechanical-quantum calculations mainly by the DFT-B88-LYP methods, DZVP basis set.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
