Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Endometriosis, Oocyte and Embryo Quality

Version 1 : Received: 6 June 2023 / Approved: 7 June 2023 / Online: 7 June 2023 (03:25:39 CEST)

A peer-reviewed article of this Preprint also exists.

Latif, S.; Saridogan, E. Endometriosis, Oocyte, and Embryo Quality. J. Clin. Med. 2023, 12, 4186. Latif, S.; Saridogan, E. Endometriosis, Oocyte, and Embryo Quality. J. Clin. Med. 2023, 12, 4186.

Abstract

Endometriosis is a common finding among women with infertility and women who are diag-nosed with endometriosis are almost twice as likely to experience infertility. Mechanisms by which endometriosis causes infertility remain poorly understood. In this review we evaluate the current literature on the impact of endometriosis on oocyte and embryo quality. The presence of endometriosis evidently reduces ovarian reserve, oocyte quality and embryo quality, however this does not appear to translate to a clear clinical impact. Analysis of data from large assisted reproduction technology registries has shown that women with endometriosis have a lower oo-cyte yield but no reduction in reproductive outcomes. There is a need for future studies in the form of well-designed randomised controlled trials to further evaluate the role of surgical and medi-cal treatment options in women with endometriosis undergoing assisted conception.

Keywords

Endometriosis; in vitro fertilization; oocytes; embryonic structures

Subject

Medicine and Pharmacology, Obstetrics and Gynaecology

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