Hepsert, S.; Dalkilic, S.; Dalkilic, L.K.; Ugurlu, F.M.; Atessahin, D.A.; Pala, R.; Kilic, Y. Anaerobic Exercise Significantly Increased Glut4 Gene Expression in Muscle Tissue of Diabetic Rats. Preprints2023, 2023060420. https://doi.org/10.20944/preprints202306.0420.v1
APA Style
Hepsert, S., Dalkilic, S., Dalkilic, L.K., Ugurlu, F.M., Atessahin, D.A., Pala, R., & Kilic, Y. (2023). Anaerobic Exercise Significantly Increased Glut4 Gene Expression in Muscle Tissue of Diabetic Rats. Preprints. https://doi.org/10.20944/preprints202306.0420.v1
Chicago/Turabian Style
Hepsert, S., Ragip Pala and Yakup Kilic. 2023 "Anaerobic Exercise Significantly Increased Glut4 Gene Expression in Muscle Tissue of Diabetic Rats" Preprints. https://doi.org/10.20944/preprints202306.0420.v1
Abstract
Diabetes is a chronic condition that worsens living conditions and causes significant problems, particularly in the vascular system. Many different treatment options are used to prevent these negative effects of diabetes. The most important of these is changing living conditions and exercising regularly.This study aimed todetermining the impacts of a 6-week anaerobic exercise protocol on the blood glucose levels and Glut4 gene expression in the muscle tissues of streptozocin (STZ)-induced diabetic rats. A total of 45 rats were separate control, sedentary, and exercise groups (n=15 each). The STZ used to induce diabetes in rats was applied once with a single intraperitoneal injection. No diabetes was created in the control group, and no exercise was performed, whereas in the sedentary group, diabetes was induced, and no exercise was applied. It was determined that the Glut4 gene expression in the muscle tissue of the exercise group was importantly increased when compared with the sedentary diabetes group.Glut4 gene is an important gene involved in blood glucose regulation and anaerobic exercise significantly increased the expression level of this gene in our study.
Biology and Life Sciences, Endocrinology and Metabolism
Copyright:
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