Preprint Brief Report Version 1 Preserved in Portico This version is not peer-reviewed

A Non-electrolysis Bioelectric Effect for Gingivitis and Hygiene Contamination Biofilm Removal

Young Wook Kim
* ORCID logo ,
Jihyun Lee
ORCID logo ,
Sang Kuy Han
ORCID logo ,
Bon-Sang Koo
,
Taeguen Park
,
Hyun Mok Park
,
Byoungdoo Lee
Version 1 : Received: 1 June 2023 / Approved: 2 June 2023 / Online: 2 June 2023 (09:48:55 CEST)

A peer-reviewed article of this Preprint also exists.

Kim, Y.W.; Lee, J.; Han, S.K.; Koo, B.-S.; Park, T.; Park, H.M.; Lee, B. A Non-Electrolysis Bioelectric Effect for Gingivitis and Hygiene Contamination Biofilm Removal. Appl. Microbiol. 2023, 3, 675-686. Kim, Y.W.; Lee, J.; Han, S.K.; Koo, B.-S.; Park, T.; Park, H.M.; Lee, B. A Non-Electrolysis Bioelectric Effect for Gingivitis and Hygiene Contamination Biofilm Removal. Appl. Microbiol. 2023, 3, 675-686.

Abstract

Bioelectric effect is known as combinatorial biofilm treatment with low dose of antibiotics with small electricity. When external electric field or current are applied, biofilms can be affected by the electrostatic force, non-uniform distribution of essential electrolytes, induction of low activity of enzyme, and increase of permeability of biofilms. In this work, we have focused on the reduction of applied electric power consumption that could avoid water electrolysis which was one of major challenges for biomedical applications. We have developed a new type of electrical signal that enhances the efficacy of biofilm removal. The results show combination of alternating and direct current remove biofilm effectively without causing electrolysis. We further developed an oral healthcare device as a bioelectric toothbrush and tested in dental clinic. The results demonstrated 75% reduction of gingivitis. In addition, we have tested a mimicked air conditioner biofilms that are root causes of aerobic hygiene infection. The result demonstrates 81.8% increased biofilm removal. In conclusion, a new bioelectric technology has been developed and demonstrated the biofilm removal efficacy without the electrolysis.

Keywords

biofilms; bioelectric effect; electrolysis; plaque index; gingival index

Subject

Biology and Life Sciences, Life Sciences

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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